基于微球透镜的任选区高分辨光学显微成像新方法研究

doi:10.7498/aps.62.034207

摘要
图/表
参考文献(13)
相关文章 (15)

全文: PDF (5433 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要提出和发展了基于毛细管-微球组合探针的任选区、高分辨显微成像新方法. 建立了微球显微成像的物理模型, 利用成像理论,推导出微球成像的放大倍率; 采用3.0, 4.4, 5.6, 7.5, 10.0 μm等不同直径的SiO₂微球, 对未经刻录的DVD光盘进行了微球显微成像实验, 可以观察到DVD光盘的微纳米结构被明显放大且对比度显著提高, 与理论计算结果相符合; 采用毛细管微探针操纵微球的方法, 实现了基于微球透镜阵列的样品微纳米结构的高分辨显微成像; 在此基础上, 进一步将毛细管微探针与微球组合, 制备出毛细管-微球组合型探针, 首次实现了基于微球透镜的样品任意区域高分辨显微成像.

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	王淑莹
	章海军
	张冬仙

关键词 ：微球, 显微成像, 毛细管-微球组合探针, 高分辨

Abstract：In this paper, we propose a novel location-free high-resolution optical microscopic imaging method based on micropipette-microsphere combined probe. According to optical principle, a physical model is established to determine the value of magnification. With SiO₂ microspheres of different diameters such as 3.0, 4.4, 5.6, 7.5 and 10.0 μm, microscopic imaging experiments are carried out. The results show that the microstructure of un-etched DVD disk can be significantly magnified and the image contrast is obviously improved, which is consistent well with the theoretical calculation. Microscopic imaging of microstructures based on SiO₂ microsphere array is realized by controlling the microspheres with a micropipette. Furthermore, a kind of micropipette-microsphere combined probe is prepared, by which location-free high-resolution optical microscopic imaging has implemented for the first time.

Key words： microsphere microscopic imaging micropipette-microsphere combined probe high-resolution

收稿日期: 2012-06-19

PACS:	42.79.Bh	(Lenses, prisms and mirrors)
	42.30.Va	(Image forming and processing)
	07.79.-v	(Scanning probe microscopes and components)
	42.40.Lx	(Diffraction efficiency, resolution, and other hologram characteristics)

基金资助:国家自然科学基金(批准号: 51077117, 11179026 )和浙江省自然科学基金(批准号: Z1110196)资助的课题.

引用本文:

王淑莹, 章海军, 张冬仙. 基于微球透镜的任选区高分辨光学显微成像新方法研究[J]. 物理学报, 2013, 62(3): . doi:10.7498/aps.62.034207.

Cite this article:

Wang Shu-Ying, Zhang Hai-Jun, Zhang Dong-Xian. Location-free optical microscopic imaging method with high-resolution based on microsphere superlenses. Acta Phys. Sin, 2013, 62(3): . doi:10.7498/aps.62.034207.

链接本文:

http://wulixb.iphy.ac.cn/CN/10.7498/aps.62.034207 或 http://wulixb.iphy.ac.cn/CN/Y2013/V62/I3/34207

[1]	Coene W, Janssen G 1992 Phys. Rev. Lett. 69 3743
[2]	Reimer L 2000 Scanning Electron Microscopy (Berlin: Springer-Verlag) p12
[3]	Binnig G, Rohrer H 1982 Helev Phys. Acta 55 726
[4]	Binnig G, Quate C F, Gerber C 1986 Phys. Rev. Lett. 56 930
[5]	Betzig E, Trautman J K 1992 Science 257 189
[6]	Ziela R, Hausa A, Tulkeb A 2008 J. Membrane Sci. 323 241
[7]	Xiao B, Feng J, Chen J C, Yan J K, Gan G Y 2008 Acta Phys. Sin. 57 3769 (in Chinese) [肖冰, 冯晶, 陈敬超, 严继康, 甘国友 2008 物理学报 57 3769]
[8]	Shi B, Zhang H J, Wu L, Zhang D X 2012 Spectrosc. Spect. Anal. 32 993 (in Chinese) [史斌, 章海军, 吴兰, 张冬仙 2012 光谱学与光谱分析 32 993]
[9]	Fu X, Zhang H J, Zhang D X 2011 Microsc. Res. Techniq. 74 1058
[10]	Wang Z Y, Li Q, Zhao J, Guo J H 2000 Acta Phys. Sin. 49 1959 (in Chinese) [王子洋, 李勤, 赵钧, 郭继华 2000 物理学报 49 1959]
[11]	Melville D O S, Blaikie R J 2005 Opt. Express 13 2127
[12]	Zhi S T, Zhang H J, Zhang D X 2011 Acta Phys. Sin. 61 024207 (in Chinese) [支绍韬, 章海军, 张冬仙 2011 物理学报 61 024207]
[13]	Wang Z B, Guo W, Li L, Boris L Y C, Khan A, Liu Z, Chen Z, Hong M 2011 Nat. Commun. 2 218