As one of important and effective means for modifying the ionosphere, chemical release can produce artificial ionospheric holes attributed to ionization depletion, which also greatly affect the short-wave propagation. In this paper, a neural gas multi-point release dynamics model is proposed baseed on mono-point one, and then the morphological control effects of chemical substances, releasing altitude, releasing mode and mass on artificial ionospheric hole are discussed. Furthermore, the short-wave propagation effect of artificial ionospheric hole is simulated and investigated by the 3-D numerical ray tracing.