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Abstract: A new scheme is proposed to suppress the meandering spiral waves in the excitable media, which is described with two-dimensional variables. An external electronic signal with stochastic phase is imposed on a local area; few grids of the system are perturbed, for example, 4×4 and/or 5×5 grid nodes among all the 256×256 nodes, so that a new target wave may occur and competition between the newly generated target wave and the intrinsic meandering spiral waves develops dynamically. The numerical simulation results confirm that it is effective to suppress the meandering spiral wave in the Barkley model. Compared with a simple periodical driving in a local area, it shows some advantages such as shorter transient period to kill the spiral wave, and it is robust to spatiotempaoral noise. A new target wave could come into being and will kill the meandering spiral wave even in the anisotropic media,of which the diffusion coefficient is a function of space, when the intensity of the spatiotemporal noise is not too strong.