This compound (C22H18O2ClBr) is monoclinic, with space group P21/n and α = 19.502(10)?, b = 9.118(5)?, c = 11.233(6)?, β = 88.18(1)?. The structure was determined by MULTAN-80. First, the bromine atom was located on the .E-map and the remaining 26 non-hydrogen atoms were determined by weighted Fourier synthesis. The atomic parameters were refined isotropically and anisotropically for two cycles respectively, then all the hydrogen atoms were located in the subsequent difference synthesis. Full matix least square refinement was made with the non-hydrogen atoms anisotropically and hydrogen atoms isotropically, to a final discrepency factor of R = 0.0776.