This paper presents the results of inves'igation on the influence of HF, HC1, H2SO4 and HAC on the liquid crystal structure of phosph tidyle-thandamine(PE) by means of the me-thod of small angle x-ray scattering method. The experiment shows that: HF exhibits the me-chanism that makes PE liquid crystal sta'e to transform into C phase; HC1 exhibits the me-chanism of transforming into LH phase; H results in La phase; and HAC results in LH phase via La phase.