In this paper we study the indirect upconversion-sensitization luminescence of Tm(0.1)Yb(10.9)：oxyfluoride glass induced by 800nm diode laser. Through the comparison between Tm(0.1)Yb(10.9)：oxyfluoride and Tm(0.1)Yb(3)：ZBLAN glasses we found that the upconversion luminescence intensity of Tm(0.1)Yb(10.9)：oxyfluoride glass was greatly enhanced and exceeded the level of Tm(0.1)Yb(3)：ZBLAN glass under the condition of indirect upconversion-sensitization. The results illustrated that under this kind of upconversion mechanism, it is possible to find some kind of material which has higher rare earth doped concentration and cut-off phonon energy, thus showing much higher upconversion efficiency than ZBLAN. This work and the results obtained will be helpful to promote the upconversion research to practical application. To our best knowledge, there have not been similar works published domestically and a broad.