A realspace renormalizationgroup approach is developed to calculate hopping conductivity of ThueMorse（ＴＭ） nanostructured chain. It is found that the kinds and the sizes, as well as the interface structures and lattice distortion of nanograins have a notable effect on the hopping conductivity of nanostructured systems. From the effect of the degree of random on hopping conductivity, TM chain is a system between Fibonacci and periodic sequence.