A laser interferometry method of measuring the thermal lensing of end-pumped solid-state lasers is proposed. This method provides a way easy to be carried out is real-time, having no influence on laser system, with a high spatial resolution for diagnosing thermal lensing. By this method, thermal lensing of end-pumped Nd:YVO4 laser is studied in detail. And this work provide a means for studying the thermal effects of laser medium and designing lasers of this kind.