An experimental study of supercontinuum generation in a photonic crystal fiber with zero dispersion wavelength 780?nm by femtosecond laser and its dependence factor is presented. Supercontinuum light with a spectrum more than one octave broad (500-1100?nm) was generated in a photonic crystalfiber by femtosecond pulses from a selfstarting, selfmode locked Ti:sapphire oscillator running at center wavelength of 810-840?nm. Different supercontinuums were generated by the 35?fs pulses with different power, central wavelength, prechirp, and the continuous noise in the femtosecond pulses. Some reasonable analysis result is obtained from the comparisons of the experimental results, and the mechanism of the supercontinuum generation is analyzed.