The property of fractional spin of the O(3) nonlinear sigma model with Hopf and Maxwell_Chern_Simons (MCS) terms is studied. According to the rule of path integral quantization for a constrained Hamilton system in Faddeev_Senjanovic sc heme，the system is quantized. Based on the quantal Noether theorem，we get the quantal conserved angular momentum, and the fractional spin at the quantum level of this system is presented.