Molecular dynamics simulations are carried out to investigate the velocity slip phenomenom of liquid flow in nanochannels. The liquid is argon, and the wall is taken to be platinum or its model solids. The effect of the surface wettability on the velocity slip is obtained through varying the potential interaction strength between the liquid and the wall. The simulation results show that the liquid adjacent to a hydrophilic surface is solid-like and has high density and orderliness. However, the liquid near a hydrophobic surface forms a gap of low density. The velocity slip of the liquid flow over solids decreases with the increasing interaction strength between the liquid and the channel surface. The slip, the no-slip and the negative slip are all possible to take place for different liquid-surface wettabilities. We find that the apparent slip of the liquid flow over solids is affected by the integrated factors of boundary slip, liquid sticking and liquid-internal slip.