Fusion barriers have been calculated for different orientations of the axial symmetry axis of deformed projectile-and target-nucleus. Using the concept of dinuclear system, considering the strong competition between fusion and quasifission processes, by solving the master equation numerically to calculate the fusion probability of superheavy nuclei, we have estimated the dependence of the fusion probabilities for 76Ge+208Pb and 48Ca+244Pu on the orientation angles of the symmetry axis of projectile-and target-nucleus, which shows that belly-belly is the most favorable orientation for synthesizing superheavy nuclei.