LaF3: Er, Yb nanoparticles doped organic-inorganic hydrid material waveguide amplifier is fabricated. The optical gain and upconversion in the waveguide are studied. The upconversion emission bands at 405,520,544 and 650?nm are assigned to 2H9/2→4I15/2，2H11/2→4I15/2，4S3/2→4I15/2 and 4F9/2→4I15/2 transitions, respectively. The possible upconversion mechanism of Er3+ in this material was analyzed. A 155 dB/cm relative gain was observed when pumped by a 976?nm laser at 160 mW power.