The intermolecular interaction potential developed in our previous research and close-coupling method are applied to the HI-He system, and the differential cross sections, partial cross sections （PCSs） and integral cross sections （ICSs） at the incident energies from 1 to 140?meV are calculated. The reliability of the interaction potential for He-HI system and the close-coupling calculations have been verified by comparing with the PCSs of He-HX （X=F, Cl, Br） systems. The results show: （1） The probability at small scattering angles is larger than that for large scattering angles. With the increase of collision energy, the scattering probability and the tail effect fall down. （2） Total ICSs mainly come from the elastic collisions. The transitions of 00 → 01and 02 contribute to the total inelastic ICSs predominantly.