The solar cells based on the blend of MEH-PPV(poly(2-methoxy-5-(2′-ethylhexoxy)- 1,4-phenylene vinylene) as donor and TiO2 nanorods as acceptor were fabricated. We analyzed the cause of performance change of the device in detail by the ultraviolet-visible absorption spectroscopy(UV-vis), photoluminescence spectroscopy(PL), the current density-voltage(J-V) curve. When TiO2 nanorods are dispersed in a polymer matrix, the performance of the device is greatly enhanced. The highest efficiency is achieved for the 1∶3 (MEH-PPV: TiO2 nanorods) weight ratio composition. We get an open circuit voltage of 0.7V, short circuit current density of 0.41 mA/cm2 and fill factor of 31.8% under air-mass 1.5 solar simulator illumination, yielding a 0.091% power conversion efficiency (PCE)，which is a nearly 60 times enhancement over the PCE of the device based on the MEH-PPV as active layer. The device PCE is further increased twofold by refluxing in phenthiol.