The paper established the motion equation of two-bubble walls under the sound field, and obtained the resonant frequency, vibration radius and radiation pressure of the double-bubble cavitation. From the frequency equation, radius of vibration and sound pressure equation we can see that the movement of two-bubble is different from a single bubble. Resonance frequency, resonance amplitude and radiation pressure are related to the distance between the bubble. By carrying out the numerical solution by MATLAB, we found that the resonance frequency and amplitude resonance increased with the distance between the two-bubble.