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中国物理学会期刊

关联白噪声对抗肿瘤体系免疫效果的影响

CSTR: 32037.14.aps.58.97

Influence of correlated white noises on the immunity of an anti-tumor system

CSTR: 32037.14.aps.58.97
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  • 在免疫监视的Logistic肿瘤生长动力学模型中引入关联的乘性白噪声,并考虑抗肿瘤体系的免疫系统激活阈值存在差异,对上述动力学生长方程进行数值仿真计算.发现噪声关联强度能够调节抗肿瘤体系个体的免疫效果,但调节的结果存在差异;噪声关联强度λ的取值存在一个最佳区间,在该区间内更多的抗肿瘤体系个体能实现最大免疫效果.

     

    We introduced two correlated Gaussian multiplicative white noises into the Logistic growth model for an anti-tumor system subject to immune surveillance. Considering various active thresholds to initiate the immunity of the anti-tumor system, we made numerical simulations to investigate how the intensity λ of two correlated white noises influences the immune effect of an anti-tumor system. Our numerical results reveal that the correlation intensity λ has an optimal value, at which the anti-tumor system will achieve functionally the best immunity.

     

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