In the NiTi shape memory alloys (SMAs), the macro-mechanical deformations and the microstructural evolutions at different strain-rates (0.001-1200 s-1) are investigated. It is found that the detwinning stress of martensitic twin increases with strain-rate increasing, which indicates that the detwinning stress has the positive strain-rate dependence. A large number of detwinning regions are found in the NiTi specimen which is deformed at the strain-rate of 10 s-1 under tension. However, with the strain-rate further increasing up to 100 s-1 and 1200 s-1, no detwinning region is observed and many twins still exist. It is shown that the detwinning rates of martensitic twin in NiTi SMAs are in a range of 10-100 s-1. Simultaneously, thermally-induced austenite is detected in the NiTi specimens deformed at high strain-rates (≥qslant10 s-1). It is ascribed to the fact that there is a change from the isothermal process to the adiabatic process when the tensile strain-rate goes up to a critical value. Additionally, a small shoulder peak is detected in differential scanning calorimeter peak of 1200 s-1 strain-rate specimen, indicating that the two-stage phase transformation occurs.