Based on the simulation of large eddy current, combined with the high-precision computational scheme, the study of planar shock wave and reflected shock waves at different reflected distances, which interact with spherical SF6 bubbles, is carried out numerically in 3D. Our numerical results show clearly the deformation of spherical interface that is induced by the Richtmyer-Meshkov instability due to the collision of shock wave. Jets induced by incident shock wave and reflected shock waves are revealed, and the flow field of the interactions between the reflected shock waves at different reflected distances and the SF6 bubbles is also discussed in detail.