The Br model is considered. The influence of the defect, defined by failure of the diffusion effect, on dynamics of spiral wave is investigated by introducing in to the system some defects. These defects are uniformly distributed. It was found numerically that these defects can lead to the reduction of the excitability of medium and the wave speed. When the number of defects is large enough, these defects can induce the meandering or the breakage of an originally stable spiral wave. On the other hands, the defects can yet cause an unstable spiral wave to become a rigidly rotating or meandering spiral wave. The phenomenon that Doppler effect causes unstable spiral wave to break up into co-existing states of spatiotemporal chaos and small spiral waves is observed for the first time. The physical mechanism of these phenomena are briefly discussed.