-
In this paper, we develop a new method to eliminate the background noise in the image of biomacromolecule with complex conformation in order to obtain highly effective and accurately quantitative information. By using this algorithm, we are able to deal with the atomic force microscopic imags of both linear DNA and branch DNA. Furthermore, our method can be extended to the study of the images in the other field.
-
Keywords:
- atomic force microscopy (AFM) /
- image analysis /
- DNA
[1] Rivetti C, Guthold M, Bustamante C 1996 J. Mol. Biol. 264 919
[2] Wei Z Y, Zang L H, Li M, Fan W, Xu Y J 2005 Acta Phys. Sin. 54 4955(in Chinese)[魏志勇、臧黎慧、李 明、范 我、许玉杰 2005 物理学报 54 4955]
[3] Rivetti C, Guthold M, Bustamante C 1999 EMBO J. 18 4464
[4] Rivetti C, Codeluppi S 2001 Ultramicroscopy 87 55
[5] Meng X, Benson K, Chada K, Huff E J, Schwartz D C 1995 Nat. Genet. 9 432
[6] Liu Y Y, Don S X, Wang P Y, Xie P, Wang W C 2005 Acta Phys. Sin. 54 622(in Chinese)[刘玉颖、窦硕星、王鹏业、谢 平、王渭池 2005 物理学报 54 622]
[7] Hamon L, Pastre D, Dupaigne P, Le Breton C, Le Cam E, Pietrement O 2007 Nucleic Acids Res. 35 e58
[8] Ratcliff G C, Erie D A 2001 J. Am. Chem. Soc. 123 5632
[9] Kada G, Kienberger F, Hinterdorfer P 2008 Nano Today 3 12
[10] Hu H L, Zhang K, Wang Z X, Kong T, Hu Y, Wang X P 2007 Acta Phys. Sin. 56 1674(in Chinese)[胡海龙、张 琨、王振兴、孔 涛、胡 颖、王晓平 2007 物理学报 56 1674]
[11] Fan K Q, Jia J Y, Zhu Y M, Liu X Y 2007 Acta Phys. Sin. 56 6345(in Chinese)[樊康旗、贾建援、朱应敏、刘小院 2007 物理学报 56 6345]
[12] Zuccheri G, Dame R T, Aquila M, Muzzalupo I, Samori B 1998 Appl. Phys. A: Mater. Sci. Process. 66 S585
[13] Lysetska M, Knoll A, Boehringer D, Hey T, Krauss G, Krausch G 2002 Nucleic Acids Res. 30 2686
[14] Wiggins P A, Van der Heijden T, Moreno-Herrero F, Spakowitz A, Phillips R, Widom J, Dekker C, Nelson P C 2006 Nat. Nanotechnol. 1 137
[15] Ficarra E, Benini L, Macii E, Zuccheri G 2005 IEEE Trans. Inf. Technol. Biomed. 9 508
[16] Sanchez-Sevilla A, Thimonier J, Marilley M, Rocca-Serra J, Barbet J 2002 Ultramicroscopy 92 151
[17] Solis F J, Bash R, Yodh J, Lindsay S M, Lohr D 2004 Biophys. J. 87 3372
[18] Wang H, Bash R, Lindsay S M, Lohr D 2005 Biophys. J. 89 3386
-
[1] Rivetti C, Guthold M, Bustamante C 1996 J. Mol. Biol. 264 919
[2] Wei Z Y, Zang L H, Li M, Fan W, Xu Y J 2005 Acta Phys. Sin. 54 4955(in Chinese)[魏志勇、臧黎慧、李 明、范 我、许玉杰 2005 物理学报 54 4955]
[3] Rivetti C, Guthold M, Bustamante C 1999 EMBO J. 18 4464
[4] Rivetti C, Codeluppi S 2001 Ultramicroscopy 87 55
[5] Meng X, Benson K, Chada K, Huff E J, Schwartz D C 1995 Nat. Genet. 9 432
[6] Liu Y Y, Don S X, Wang P Y, Xie P, Wang W C 2005 Acta Phys. Sin. 54 622(in Chinese)[刘玉颖、窦硕星、王鹏业、谢 平、王渭池 2005 物理学报 54 622]
[7] Hamon L, Pastre D, Dupaigne P, Le Breton C, Le Cam E, Pietrement O 2007 Nucleic Acids Res. 35 e58
[8] Ratcliff G C, Erie D A 2001 J. Am. Chem. Soc. 123 5632
[9] Kada G, Kienberger F, Hinterdorfer P 2008 Nano Today 3 12
[10] Hu H L, Zhang K, Wang Z X, Kong T, Hu Y, Wang X P 2007 Acta Phys. Sin. 56 1674(in Chinese)[胡海龙、张 琨、王振兴、孔 涛、胡 颖、王晓平 2007 物理学报 56 1674]
[11] Fan K Q, Jia J Y, Zhu Y M, Liu X Y 2007 Acta Phys. Sin. 56 6345(in Chinese)[樊康旗、贾建援、朱应敏、刘小院 2007 物理学报 56 6345]
[12] Zuccheri G, Dame R T, Aquila M, Muzzalupo I, Samori B 1998 Appl. Phys. A: Mater. Sci. Process. 66 S585
[13] Lysetska M, Knoll A, Boehringer D, Hey T, Krauss G, Krausch G 2002 Nucleic Acids Res. 30 2686
[14] Wiggins P A, Van der Heijden T, Moreno-Herrero F, Spakowitz A, Phillips R, Widom J, Dekker C, Nelson P C 2006 Nat. Nanotechnol. 1 137
[15] Ficarra E, Benini L, Macii E, Zuccheri G 2005 IEEE Trans. Inf. Technol. Biomed. 9 508
[16] Sanchez-Sevilla A, Thimonier J, Marilley M, Rocca-Serra J, Barbet J 2002 Ultramicroscopy 92 151
[17] Solis F J, Bash R, Yodh J, Lindsay S M, Lohr D 2004 Biophys. J. 87 3372
[18] Wang H, Bash R, Lindsay S M, Lohr D 2005 Biophys. J. 89 3386
计量
- 文章访问数: 9300
- PDF下载量: 832
- 被引次数: 0