分布式电流刺激抑制心肌组织中螺旋波

王春妮; 马军

doi:10.7498/aps.62.084501

摘要

利用两种恒定电信号刺激介质不同区域来产生分布式电流, 外界分布式电流内化为跨膜电流后在介质中形成稳定的梯度力可抑制螺旋波的传播. 当螺旋波被消除后系统进一步演化为均匀态且对应的膜片电位采样序列逐渐趋于一个稳定值. 在考虑噪声情况下, 该方法仍然能消除螺旋波, 对其采样序列分析也验证了方法的可靠性.

关键词:

Forcing currents are generated by using two types of constant currents to stimulate different areas of a medium. The external current is mapped into transmembrane current and stable gradient force is induced to drive the stable rotating spiral wave. The medium becomes homogeneous when the spiral wave is removed and the time series of sampled membrane potentials becomes stable value without considering noise. The scheme is confirmed to be effective in the presence of Gaussian white noise.

Keywords:

作者及机构信息

王春妮,
马军

1.
兰州理工大学物理系, 兰州 730050

基金项目: 国家自然科学基金(批准号:11265008)资助的课题.

Authors and contacts

1.
Department of Physics, Lanzhou University of Technology, Lanzhou 730050, China

Funds: Project supported by the National Natural Science Foundation of China (Grant No. 11265008).

参考文献

[1]	Hagan P S 1982 SIAM J. Appl. Math. 42 762
[2]	Braune M, Engel H 1993 Chem. Phys. Lett. 204 257
[3]	Nettesheim S, von Oertzen A, Rotermund H H, Ertl G 1993 J. Chem. Phys. 98 9977
[4]	Koch A J, Meinhardt H 1994 Rev. Mod. Phys. 66 1481
[5]	Barkley D 1994 Phys. Rev. Lett. 72 164
[6]	Merzhanov A G, Rumanov E N 1999 Rev. Mod. Phys. 71 1173
[7]	Meron E, Pelcé P 1988 Phys. Rev. Lett. 60 1880
[8]	Barkley D 1992 Phys. Rev. Lett. 68 2090
[9]	Amemiya T, Kádár S, Kettunen P, Showalter K 1996 Phys. Rev. Lett. 77 3244
[10]	Scott S, Wang J Showalter K 1997 J. Chem. Soc. Faraday. Trans. 93 1733
[11]	Starobin J M, Starmer C F 1997 Phys. Rev. E 55 1193
[12]	Osipov G V, Shulgin B V, Collins J J 1998 Phys. Rev. E 58 6955
[13]	LeBlanc V, Wulff C 2000 J. Nonlinear Sci. 10 569
[14]	Zhou L Q, Ouyang Q 2000 Phys. Rev. Lett. 85 1650
[15]	Fenton F H, Cherry E M, Hastings H M 2002 Chaos 12 852
[16]	Ashwin P, Melbourne I, Nicol M 2001 Physica D 156 364
[17]	Sandstede B, Scheel A 2001 Phys. Rev. Lett. 86 171
[18]	Sandstede B, Scheel A 2000 Phys. Rev. E 62 7708
[19]	Mikhailov A S, Showalter K 2006 Phys. Rep. 425 79
[20]	Vanag V K, Epstein I R 2001 Science 294 835
[21]	Henry H 2004 Phys. Rev. E 70 026204
[22]	Steinbock O, Mller S C, Zykov V S 1993 Nature 366 322
[23]	Rohlf K, Glass L, Kapral R 2006 Chaos 16 037115
[24]	Biktashev V N, Holden A V 1996 Proc. R. Soc. Lond. B 263 1373
[25]	Biktashev V N, Holden A V 1998 Chaos 8 48
[26]	Qu Z L, Xie F G, Garfinkel A, Weiss N J 2000 Ann. Biomed. Eng. 28 755
[27]	Xie F, Qu Z, Garfinkel A, Weiss J N 2002 Am. J. Physiol. Heart Circ. Physiol. 283 H448
[28]	Nash M P, Panfilov A V 2004 Progr. Biophys. Mol. Biol. 85 501
[29]	Honjo H, Yamazaki M, Kamiya K, Kodama I 2007 Circ. J. 71 (Suppl. A) A26
[30]	Panfilov A V, Mller S C, Zykov V S 2000 Phys. Rev. E 61 4644
[31]	Stamp A T, Osipov G V, Collins J J 2002 Chaos 12 931
[32]	Ashihara T, Namba T, Ito M, Ikeda T, Nakazawa K, Trayanova N 2004 J. Cardiovasc. Electrophysiol. 15 226
[33]	Ma J, Ying H P, Li Y L 2007 Chin. Phys. 16 955
[34]	Weise L D, Panfilov A V 2011 PLoS ONE 6 e27264
[35]	Shajahan T K, Nayak A R, Pandit R 2009 PLoS ONE 4 e4738
[36]	Cysyk J, Tung L 2008 Biophys. J. 94 1533
[37]	Ouyang Q 2000 Pattern Formation in Reaction-Diffusion Systems (Shanghai:Shanghai Scientific & Technological Education Publishing House) pp73-77 (in Chinese) [欧阳颀 2000 反应扩散系统中的斑图动力学(上海:上海科技教育出版社)第73–77页]
[38]	Zhang H, Cao Z J, Wu N J, Ying H P, Hu G 2005 Phys. Rev. Lett. 94 188301
[39]	Cao Z J, Li P F, Zhang H, Xie F G, Hu G 2007 Chaos 17 015107
[40]	Gao X, Feng X, Cai M C, Li B W, Ying H P, Zhang H 2012 Phys. Rev. E 85 016213
[41]	Deng L Y, Zhang H, Li Y Q 2010 Phys. Rev. E 86 016204
[42]	Wu N J, Zhang H, Ying H P, Cao Z J, Hu G 2006 Phys. Rev. E 73 060901
[43]	Nie H C, Gao J H, Zhan M 2011 Phys. Rev. E 84 056204
[44]	Zhan M, Zou W, Liu X 2010 Phys. Rev. E 81 036211
[45]	Zhan M, Luo J M, Gao J H 2007 Phys. Rev. E 75 016214
[46]	Yang J Z, Xie F G, Qu Z L, Garfinkel A 2003 Phys. Rev. Lett. 91 148302
[47]	Yang J Z, Zhang M 2006 Phys. Lett. A 352 69
[48]	Yang J Z, Garfinkel A 2003 Phys. Rev. E 68 066312
[49]	Gu G F, L Y P, Tang G N 2010 Chin. Phys. B 19 050515
[50]	Chen X J, Tian T T, Zhou Z W, Hu Y B, Tang G N 2012 Acta Phys. Sin. 61 210509 (in Chinese) [陈醒基, 田涛涛, 周振玮, 胡一博, 唐国宁2012物理学报 61 210509]
[51]	Zhou Z W, Chen X J, Tian T T, Tang G N 2012 Acta Phys. Sin. 61 210506 (in Chinese) [周振玮, 陈醒基, 田涛涛, 唐国宁 2012物理学报 61 210506]
[52]	Kuang Y L, Tang G N 2012 Acta Phys. Sin. 61 190501 (in Chinese) [邝玉兰, 唐国宁2012物理学报 61 190501]
[53]	Li G Z, Chen Y Q, Tang G N, Liu J X 2011 Chin. Phys. Lett. 28 020504
[54]	Kuang Y L, Tang G N 2012 Acta Phys. Sin. 61 100504 (in Chinese) [邝玉兰, 唐国宁2012物理学报 61 100504]
[55]	Dong L F, Wang H F, Liu F C, He Y F 2007 New J. Phys. 9 330
[56]	He Y F, Liu F C, Fan W L, Dong L F 2012 Chin. Phys. B 21 034701
[57]	Dong L F, Bai Z G, He Y F 2012 Acta Phys. Sin. 61 120509 (in Chinese) [董丽芳, 白占国, 贺亚峰2012物理学报 61 120509]
[58]	Chen J X, Xu J R, Yuan X P, Ying H P 2009 J. Phys. Chem. B 113 849
[59]	Chen J X, Zhang H, Li Y Q 2009 J. Chem. Phys. 130 124510
[60]	Chen J X, Mao J W, Hu B, Xu J R, He Y F, Li Y, Yuan X P 2009 Phys. Rev. E 79 066209
[61]	Yuan G Y 2011 Chin. Phys. B 20 040503
[62]	Yuan G Y, Yang S P, Wang G R, Chen S G 2008 Chin. Phys. B 17 1925
[63]	Yuan G Y, Xu L, Xu A G, Wang G R, Yang S P 2011 Chaos, Soliton. Fract. 44 728
[64]	Qian Y 2012 Chin. Phys. B 21 088201
[65]	Qian Y, Wang C J, Shi H S 2010 Chin. Phys. B 20 108201
[66]	Qian Y, Huang X D, Liao X H 2010 Chin. Phys. B 19 050513
[67]	Ma J, Ying H P, Pan G W, Pu Z S 2005 Chin. Phys. Lett. 22 2176
[68]	Ma J, Wu Y, Ying H P, Jia Y 2011 Chin. Sci. Bull. 56 151
[69]	Ma J, Tang J, Zhang A H, Jia Y 2010 Sci. China Phys. Mech. Astro. 53 172
[70]	Ma J, Tang J, Zhang A H, Jia Y 2010 J. Biol. Syst. 18 243
[71]	Huang L, Ma J, Tang J, Li F 2013 J. Biol. Syst. 21 1350002
[72]	Ma J, Huang L, Ying H P, Pu Z S 2012 Chin. Sci. Bull. 57 2094
[73]	Ma J, Tang J, Wang C N, Jia Y 2011 Int. J. Bifur. Chaos 21 587
[74]	Aliev R R, Panfilov A V 1996 Chaos, Soliton. Fract. 293 965
[75]	Purmir A, Krinsky V I 1996 Physica D 91 205
[76]	Keener J P 1996 J. Theor. Biol. 178 313
[77]	Purmir A, Krinsky V I 1997 J. Theor. Biol. 185 189

施引文献

[1]	Hagan P S 1982 SIAM J. Appl. Math. 42 762
[2]	Braune M, Engel H 1993 Chem. Phys. Lett. 204 257
[3]	Nettesheim S, von Oertzen A, Rotermund H H, Ertl G 1993 J. Chem. Phys. 98 9977
[4]	Koch A J, Meinhardt H 1994 Rev. Mod. Phys. 66 1481
[5]	Barkley D 1994 Phys. Rev. Lett. 72 164
[6]	Merzhanov A G, Rumanov E N 1999 Rev. Mod. Phys. 71 1173
[7]	Meron E, Pelcé P 1988 Phys. Rev. Lett. 60 1880
[8]	Barkley D 1992 Phys. Rev. Lett. 68 2090
[9]	Amemiya T, Kádár S, Kettunen P, Showalter K 1996 Phys. Rev. Lett. 77 3244
[10]	Scott S, Wang J Showalter K 1997 J. Chem. Soc. Faraday. Trans. 93 1733
[11]	Starobin J M, Starmer C F 1997 Phys. Rev. E 55 1193
[12]	Osipov G V, Shulgin B V, Collins J J 1998 Phys. Rev. E 58 6955
[13]	LeBlanc V, Wulff C 2000 J. Nonlinear Sci. 10 569
[14]	Zhou L Q, Ouyang Q 2000 Phys. Rev. Lett. 85 1650
[15]	Fenton F H, Cherry E M, Hastings H M 2002 Chaos 12 852
[16]	Ashwin P, Melbourne I, Nicol M 2001 Physica D 156 364
[17]	Sandstede B, Scheel A 2001 Phys. Rev. Lett. 86 171
[18]	Sandstede B, Scheel A 2000 Phys. Rev. E 62 7708
[19]	Mikhailov A S, Showalter K 2006 Phys. Rep. 425 79
[20]	Vanag V K, Epstein I R 2001 Science 294 835
[21]	Henry H 2004 Phys. Rev. E 70 026204
[22]	Steinbock O, Mller S C, Zykov V S 1993 Nature 366 322
[23]	Rohlf K, Glass L, Kapral R 2006 Chaos 16 037115
[24]	Biktashev V N, Holden A V 1996 Proc. R. Soc. Lond. B 263 1373
[25]	Biktashev V N, Holden A V 1998 Chaos 8 48
[26]	Qu Z L, Xie F G, Garfinkel A, Weiss N J 2000 Ann. Biomed. Eng. 28 755
[27]	Xie F, Qu Z, Garfinkel A, Weiss J N 2002 Am. J. Physiol. Heart Circ. Physiol. 283 H448
[28]	Nash M P, Panfilov A V 2004 Progr. Biophys. Mol. Biol. 85 501
[29]	Honjo H, Yamazaki M, Kamiya K, Kodama I 2007 Circ. J. 71 (Suppl. A) A26
[30]	Panfilov A V, Mller S C, Zykov V S 2000 Phys. Rev. E 61 4644
[31]	Stamp A T, Osipov G V, Collins J J 2002 Chaos 12 931
[32]	Ashihara T, Namba T, Ito M, Ikeda T, Nakazawa K, Trayanova N 2004 J. Cardiovasc. Electrophysiol. 15 226
[33]	Ma J, Ying H P, Li Y L 2007 Chin. Phys. 16 955
[34]	Weise L D, Panfilov A V 2011 PLoS ONE 6 e27264
[35]	Shajahan T K, Nayak A R, Pandit R 2009 PLoS ONE 4 e4738
[36]	Cysyk J, Tung L 2008 Biophys. J. 94 1533
[37]	Ouyang Q 2000 Pattern Formation in Reaction-Diffusion Systems (Shanghai:Shanghai Scientific & Technological Education Publishing House) pp73-77 (in Chinese) [欧阳颀 2000 反应扩散系统中的斑图动力学(上海:上海科技教育出版社)第73–77页]
[38]	Zhang H, Cao Z J, Wu N J, Ying H P, Hu G 2005 Phys. Rev. Lett. 94 188301
[39]	Cao Z J, Li P F, Zhang H, Xie F G, Hu G 2007 Chaos 17 015107
[40]	Gao X, Feng X, Cai M C, Li B W, Ying H P, Zhang H 2012 Phys. Rev. E 85 016213
[41]	Deng L Y, Zhang H, Li Y Q 2010 Phys. Rev. E 86 016204
[42]	Wu N J, Zhang H, Ying H P, Cao Z J, Hu G 2006 Phys. Rev. E 73 060901
[43]	Nie H C, Gao J H, Zhan M 2011 Phys. Rev. E 84 056204
[44]	Zhan M, Zou W, Liu X 2010 Phys. Rev. E 81 036211
[45]	Zhan M, Luo J M, Gao J H 2007 Phys. Rev. E 75 016214
[46]	Yang J Z, Xie F G, Qu Z L, Garfinkel A 2003 Phys. Rev. Lett. 91 148302
[47]	Yang J Z, Zhang M 2006 Phys. Lett. A 352 69
[48]	Yang J Z, Garfinkel A 2003 Phys. Rev. E 68 066312
[49]	Gu G F, L Y P, Tang G N 2010 Chin. Phys. B 19 050515
[50]	Chen X J, Tian T T, Zhou Z W, Hu Y B, Tang G N 2012 Acta Phys. Sin. 61 210509 (in Chinese) [陈醒基, 田涛涛, 周振玮, 胡一博, 唐国宁2012物理学报 61 210509]
[51]	Zhou Z W, Chen X J, Tian T T, Tang G N 2012 Acta Phys. Sin. 61 210506 (in Chinese) [周振玮, 陈醒基, 田涛涛, 唐国宁 2012物理学报 61 210506]
[52]	Kuang Y L, Tang G N 2012 Acta Phys. Sin. 61 190501 (in Chinese) [邝玉兰, 唐国宁2012物理学报 61 190501]
[53]	Li G Z, Chen Y Q, Tang G N, Liu J X 2011 Chin. Phys. Lett. 28 020504
[54]	Kuang Y L, Tang G N 2012 Acta Phys. Sin. 61 100504 (in Chinese) [邝玉兰, 唐国宁2012物理学报 61 100504]
[55]	Dong L F, Wang H F, Liu F C, He Y F 2007 New J. Phys. 9 330
[56]	He Y F, Liu F C, Fan W L, Dong L F 2012 Chin. Phys. B 21 034701
[57]	Dong L F, Bai Z G, He Y F 2012 Acta Phys. Sin. 61 120509 (in Chinese) [董丽芳, 白占国, 贺亚峰2012物理学报 61 120509]
[58]	Chen J X, Xu J R, Yuan X P, Ying H P 2009 J. Phys. Chem. B 113 849
[59]	Chen J X, Zhang H, Li Y Q 2009 J. Chem. Phys. 130 124510
[60]	Chen J X, Mao J W, Hu B, Xu J R, He Y F, Li Y, Yuan X P 2009 Phys. Rev. E 79 066209
[61]	Yuan G Y 2011 Chin. Phys. B 20 040503
[62]	Yuan G Y, Yang S P, Wang G R, Chen S G 2008 Chin. Phys. B 17 1925
[63]	Yuan G Y, Xu L, Xu A G, Wang G R, Yang S P 2011 Chaos, Soliton. Fract. 44 728
[64]	Qian Y 2012 Chin. Phys. B 21 088201
[65]	Qian Y, Wang C J, Shi H S 2010 Chin. Phys. B 20 108201
[66]	Qian Y, Huang X D, Liao X H 2010 Chin. Phys. B 19 050513
[67]	Ma J, Ying H P, Pan G W, Pu Z S 2005 Chin. Phys. Lett. 22 2176
[68]	Ma J, Wu Y, Ying H P, Jia Y 2011 Chin. Sci. Bull. 56 151
[69]	Ma J, Tang J, Zhang A H, Jia Y 2010 Sci. China Phys. Mech. Astro. 53 172
[70]	Ma J, Tang J, Zhang A H, Jia Y 2010 J. Biol. Syst. 18 243
[71]	Huang L, Ma J, Tang J, Li F 2013 J. Biol. Syst. 21 1350002
[72]	Ma J, Huang L, Ying H P, Pu Z S 2012 Chin. Sci. Bull. 57 2094
[73]	Ma J, Tang J, Wang C N, Jia Y 2011 Int. J. Bifur. Chaos 21 587
[74]	Aliev R R, Panfilov A V 1996 Chaos, Soliton. Fract. 293 965
[75]	Purmir A, Krinsky V I 1996 Physica D 91 205
[76]	Keener J P 1996 J. Theor. Biol. 178 313
[77]	Purmir A, Krinsky V I 1997 J. Theor. Biol. 185 189

[1]	刘冠男, 李新霞, 刘洪波, 孙爱萍. HL-2M托卡马克装置中螺旋波与低杂波的协同电流驱动. 物理学报, 2023, 72(24): 245202. doi: 10.7498/aps.72.20231077
[2]	潘军廷, 何银杰, 夏远勋, 张宏. 极化电场对可激发介质中螺旋波的控制. 物理学报, 2020, 69(8): 080503. doi: 10.7498/aps.69.20191934
[3]	韦宾, 唐国宁, 邓敏艺. 具有早期后除极化现象的可激发系统中螺旋波破碎方式研究. 物理学报, 2018, 67(9): 090501. doi: 10.7498/aps.67.20172505
[4]	王小艳, 汪芃, 李倩昀, 唐国宁. 用晚钠电流终止心脏中的螺旋波和时空混沌. 物理学报, 2017, 66(13): 138201. doi: 10.7498/aps.66.138201
[5]	李伟恒, 潘飞, 黎维新, 唐国宁. 非对称耦合两层可激发介质中的螺旋波动力学. 物理学报, 2015, 64(19): 198201. doi: 10.7498/aps.64.198201
[6]	李伟恒, 黎维新, 潘飞, 唐国宁. 两层耦合可激发介质中螺旋波转变为平面波. 物理学报, 2014, 63(20): 208201. doi: 10.7498/aps.63.208201
[7]	陈醒基, 乔成功, 王利利, 周振玮, 田涛涛, 唐国宁. 间接延迟耦合可激发介质中螺旋波的演化. 物理学报, 2013, 62(12): 128201. doi: 10.7498/aps.62.128201
[8]	田昌海, 邓敏艺. 随机扰动对螺旋波动力学的影响研究. 物理学报, 2013, 62(19): 190503. doi: 10.7498/aps.62.190503
[9]	胡柏林, 马军, 李凡, 蒲忠胜. 神经元网络中分布式电流诱导靶波机理研究. 物理学报, 2013, 62(5): 058701. doi: 10.7498/aps.62.058701
[10]	陈醒基, 田涛涛, 周振玮, 胡一博, 唐国宁. 通过被动介质耦合的两螺旋波的同步. 物理学报, 2012, 61(21): 210509. doi: 10.7498/aps.61.210509
[11]	周振玮, 陈醒基, 田涛涛, 唐国宁. 耦合可激发介质中螺旋波的控制研究. 物理学报, 2012, 61(21): 210506. doi: 10.7498/aps.61.210506
[12]	董丽芳, 白占国, 贺亚峰. 非均匀可激发介质中的稀密螺旋波. 物理学报, 2012, 61(12): 120509. doi: 10.7498/aps.61.120509
[13]	黎广钊, 陈永淇, 唐国宁. 三层弱循环耦合可激发介质中螺旋波动力学. 物理学报, 2012, 61(2): 020502. doi: 10.7498/aps.61.020502
[14]	韦海明, 唐国宁. 离散可激发介质中早期后去极化对螺旋波影响的数值研究. 物理学报, 2011, 60(3): 030501. doi: 10.7498/aps.60.030501
[15]	田昌海, 邓敏艺, 孔令江, 刘慕仁. 螺旋波动力学性质的元胞自动机有向小世界网络研究. 物理学报, 2011, 60(8): 080505. doi: 10.7498/aps.60.080505
[16]	唐冬妮, 唐国宁. 无扩散功能的缺陷对螺旋波动力学行为的影响. 物理学报, 2010, 59(4): 2319-2325. doi: 10.7498/aps.59.2319
[17]	张立升, 邓敏艺, 孔令江, 刘慕仁, 唐国宁. 用元胞自动机模型研究二维激发介质中的非线性波. 物理学报, 2009, 58(7): 4493-4499. doi: 10.7498/aps.58.4493
[18]	张国勇, 马军, 甘正宁, 陈勇. 非均匀可激介质中的螺旋波. 物理学报, 2008, 57(11): 6815-6823. doi: 10.7498/aps.57.6815
[19]	尹小舟, 刘勇. 非连续反馈控制激发介质中的螺旋波. 物理学报, 2008, 57(11): 6844-6851. doi: 10.7498/aps.57.6844
[20]	马军, 靳伍银, 李延龙, 陈勇. 随机相位扰动抑制激发介质中漂移的螺旋波. 物理学报, 2007, 56(4): 2456-2465. doi: 10.7498/aps.56.2456

计量

文章访问数: 6351
PDF下载量: 532
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

搜索

留言板