Nano-partical sensing based on Raman laser in the whispering gallery mode microresonators

Wang Tao; Yang Xu; Liu Xiao-Fei; Lei Fu-Chuan; Gao Ming; Hu Yun-Qi; Long Gui-Lu

doi:10.7498/aps.64.164212

Abstract

In this review, the recent development of nano-particle detection using Raman lasers in the whispering gallery mode microcavities is presented. The fabrication of the microcavity, the working principles are given and the recent experimental progress is reviewed. Recent years, the demand for nano-particle sensing techniques was increased, since more and more nano-particles of sizes between 1 nm and 100 nm are employed in areas such as biomedical science and homeland security. In these applications, label-free, rapid and real-time sensing requirements are necessary. Whispering gallery mode (WGM) micro-resonators have high-quality factors and small mode volumes, and have achieved significant progress in the nano-particle sensing field. There are various measurement mechanisms for nano-particle sensing using WGM cavities, including resonance mode broadening, resonance frequency shift, and mode splitting changes. The key point to improve sensing limit is to narrow the resonance mode linewidth, which means reducing the optical cavity losses, or equivalently to enhance quality factor. An important approach to narrowing the mode linewidth is to fabricate active resonators that provide gain and produce laser by doping rare earth irons. According to Schawlow-Townes formula, the linewidth of corresponding laser will be narrower than that of the original optical cavity mode. Active resonators have outstanding performances in particle detection. However, doping process requires complex fabrication steps, and rare earth irons laser demands a certain pumping wavelength band. A new approach is to use low threshold Raman laser in an optical micro-resonator. The binding of nano-particles on WGM micro-resonator induces resonance mode splitting. Raman lasers of the two splitting modes irradiate the same photon detector and generate a beat note signal. By monitoring the jumps of the two split mode differential signals, one can easily recognize the nano-particle binding events, thus achieving real time nanoparticle detection. Using Raman laser in WGM cavities in nano-particle sensing is no longer limited by the stringent requirement of a suitable pump light source, which greatly expands the applicability of this method in different environments. It does not need additional fabrication process as compared with the rare earth doping method. It has also better biological compatibility, which makes it a promising technique in biomedical applications. Recently, two groups, i.e., Li et al. (Proc. Natl. Acad. Sci. 111 14657) from Peking University, and zdemir et al. from University of Washington and Tsinghua University, have successfully completed the demonstration experiments. zdemir et al. (Proc. Natl. Acad. Sci. 111 E3836) have achieved a nano-particle sensing limit down to 10 nm without labelling, and Li et al. (Proc. Natl. Acad. Sci. 111 14657) realized real-time detection of single nano-particles with WGM cavity Raman laser in an aqueous environment. Both experiments have shown the great potential of the new approach. The new technique can also be used in other photonic systems, such as the photonic crystal or metal materials.

Keywords:

Authors and contacts

1.
State Key Laboratory for Low-dimensional Quantum Physics, Department of Physics, Tsinghua University, Beijing 100084, China;
2.
Tsinghua National Laboratory for Information Science and Technology, Beijing 100084, China;
3.
Collaborative Innovation Center of Quantum Matter, Beijing 100084, China
Funds: Project supported by the National Natural Science Foundation of China (Grant Nos. 11175094, 11474181, 91221205) and the National Basic Research Program of China (Grant No. 2011CB9216002).

References

[1]	Szymanski W W, Nagy A, Czitrovszky A, Jani P 2002 Meas. Sci. Technol. 13 303
[2]	Van D M, Tchebotareva A, Orrit M, Lippitz M, Berciaud S, Lasne D, Cognet L, Lounis B 2006 PCCP 8 3486
[3]	Burg T P, Godin M, Knudsen S M, Shen W, Carlson G, Foster J S, Babcock K, Manalis S R 2007 Nature 446 1066
[4]	Vollmer F, Arnold S 2008 Nat. Methods 5 591
[5]	Vollmer F, Arnold S, Keng D 2008 Proc. Natl. Acad. Sci. 105 20701
[6]	Fan X, White I M, Shopova S I, Zhu H, Suter J D, Sun Y 2008 Anal. Chim. Acta 620 8
[7]	Naik A, Hanay M, Hiebert W, Feng X, Roukes M 2009 Nat. Nanotechnology 4 445
[8]	Zhu J, zdemir S K, Xiao Y F, Li L, He L, Chen D R, Yang L 2010 Nat. Photonics 4 46
[9]	He L, zdemir S K, Zhu J, Kim W, Yang L 2011 Nat. Nanotechnology 6 428
[10]	Vollmer F, Yang L
[11]	Yurt A, Daaboul G G, Connor J H, Goldberg B B, Unl M S 2012 Nanoscale 4 715
[12]	Wang W, Tao N 2013 Anal. Chem. 86 2
[13]	Colvin V L 2003 Nat. Biotechnology 21 1166
[14]	Hoet P H, Brske-Hohlfeld I, Salata O V 2004 J. Nanobiotechnology 2 12
[15]	Alivisatos P 2004 Nat. Biotechnology 22 47
[16]	Storhoff J J, Lucas A D, Garimella V, Bao Y P, Mller U R 2004 Nat. Biotechnology 22 883
[17]	Cheng M M C, Cuda G, Bunimovich Y L, Gaspari M, Heath J R, Hill H D, Mirkin C A, Nijdam A J, Terracciano R, Thundat T, Ferrari M 2006 Curr. Opin. Chem. Biol. 10 11
[18]	Sinha R, Kim G J, Nie S, Shin D M 2006 Mol. Cancer. Ther. 5 1909
[19]	De M, Ghosh P S, Rotello V M 2008 Adv. Mater. 20 4225
[20]	Smith A M, Nie S 2009 Accounts Chem. Res. 43 190
[21]	Dai S X, Lu L W, Tao G M, Xu Y S, Yin D M, Niu X K, Zhang W 2012 Laser Optoelectronics Progress. 49 080001 (in Chinese) [戴世勋, 路来伟, 陶光明, 许银生, 尹冬梅, 牛雪珂, 张巍 2012 激光与光电子学进展 49 080001]
[22]	Betzig E, Trautman J, Harris T, Weiner J, Kostelak R 1991 Science 251 1468
[23]	Zhang J, Dong L, Yu S H 2015 Sci. Bull. 60 785
[24]	Seydack M 2005 Biosens. Bioelectron. 20 245
[25]	Liu T G, Zhang F, Meng Z (in Chinese) [刘铁根, 张凡, 孟卓 2005 光学技术 31 96]
[26]	Wei Q, Qi H, Luo W, Tseng D, Ki S J, Wan Z, Grcs Z, Bentolila L A, Wu T T, Sun R, Ozcan A 2013 ACS Nano 7 9147
[27]	Plakhotnik T, Palm V 2001 Phys. Rev. Lett. 87 183602
[28]	Knollenber R G
[29]	Boyer D, Tamarat P, Maali A, Lounis B, Orrit M 2002 Science 297 1160
[30]	Lindfors K, Kalkbrenner T, Stoller P, Sandoghdar V 2004 Phys. Rev. Lett. 93 037401
[31]	Patolsky F, Zheng G, Hayden O, Lakadamyali M, Zhuang X, Lieber C M 2004 Proc. Natl. Acad. Sci. 101 14017
[32]	Choi Y, Moody I S, Sims P C, Hunt S R, Corso B L, Perez I, Weiss G A, Collins P G 2012 Science 335 319
[33]	Arlett J L, Myers E B, Roukes M L 2011 Nat. Nanotechnology 6 203
[34]	Yue X J, Hong T S, Yang Z, Huang S P 2013 Chin. Sci. Bull. 58 821
[35]	Zhang L, Song Z D 2014 Sci. China-Phys. Mech. Astron. 57 880
[36]	Lu X K, Guo M T, Su J P, Gong Q X, Wu J K, Liu J L, Chen M, Ma F Y 2013 Acta Phys. Sin. 62 084208 (in Chinese) [卢小可, 郭茂田, 苏建坡, 弓巧侠, 武进科, 刘建立, 陈明, 马凤英 2013 物理学报 62 084208]
[37]	Nie W J, Lan Y H, Li Y Zhu S Y 2014 Sci. China-Phys. Mech. Astron. 57 2276
[38]	Svedendahl M, Verre R, Kll M 2014 Light: Science Applications 3 e220
[39]	Li W F, Du J J, Wen R J, Yang P F, Li G, Zhang T C 2014 Acta. Phys. Sin. 63 244205 (in Chinese) [李文芳, 杜金锦, 文瑞娟, 杨鹏飞, 李刚, 张天才 2014 物理学报 63 244205]
[40]	Sheng Y B, Liu J, Zhao S Y, Zhou L
[41]	Du J J, Li W F, Wen R J, Li G, Zhang T C 2013 Acta Phys. Sin. 62 194203 (in Chinese) [杜金锦, 李文芳, 文瑞娟, 李刚, 张天才 2013 物理学报 62 194203]
[42]	Wang C, He L Y, Zhang Y, Ma H Q, Zhang R 2013 Sci. China-Phys. Mech. Astron. 56 2054
[43]	Arnold S, Khoshsima M, Teraoka I, Holler S, Vollmer F 2003 Opt. Lett. 28 272
[44]	Hunt H K, Armani A M
[45]	Vollmer F, Braun D, Libchaber A, Khoshsima M, Teraoka I, Arnold S 2002 Appl. Phys. Lett. 80 4057
[46]	Sun Y, Fan X 2011 Anal. Bioanal. Chem. 399 205
[47]	Armani A M, Kulkarni R P, Fraser S E, Flagan R C, Vahala K J 2007 Science 317 783
[48]	Washburn A L, Luchansky M S, Bowman A L, Bailey R C 2009 Anal. Chem. 82 69
[49]	Shopova S, Rajmangal R, Nishida Y, Arnold S 2010 Rev. Sci. Instrum. 81 103110
[50]	Lu T, Lee H, Chen T, Herchak S, Kim J H, Fraser S E, Flagan R C, Vahala K 2011 Proc. Natl. Acad. Sci. 108 5976
[51]	Santiago-Cordoba M A, Boriskina S V, Vollmer F, Demirel M C 2011 Appl. Phys. Lett. 99 073701
[52]	Zhu J, zdemir S K, He L, Chen D R, Yang L 2011 Opt. Express 19 16195
[53]	Dantham V R, Holler S, Kolchenko V, Wan Z, Arnold S 2012 Appl. Phys. Lett. 101 043704
[54]	Santiago-Cordoba M A, Cetinkaya M, Boriskina S V, Vollmer F, Demirel M C 2012 J. Biophotonics 5 629
[55]	Kim W, zdemir S K, Zhu J, Monifi F, Coban C, Yang L 2012 Opt. Express 20 29426
[56]	Yi X, Xiao Y F, Feng Y, Qiu D Y, Fan J Y, Li Y, Gong Q 2012 J. Appl. Phys. 111 114702
[57]	Lin S, Crozier K B 2013 ACS Nano 7 1725
[58]	Dantham V R, Holler S, Barbre C, Keng D, Kolchenko V, Arnold S 2013 Nano Lett. 13 3347
[59]	Swaim J D, Knittel J, Bowen W P 2013 Appl. Phys. Lett. 102 183106
[60]	Shao L, Jiang X F, Yu X C, Li B B, Clements W R, Vollmer F, Wang W, Xiao Y F, Gong Q 2013 Adv. Mater. 25 5616
[61]	Knittel J, Swaim J D, McAuslan D L, Brawley G A, Bowen W P 2013 Sci. Rep. 3 2947
[62]	Wang T, Cao C, Wang C 2013 Sci. China Inform. Sci. 56 1
[63]	Shopova S, Rajmangal R, Holler S, Arnold S 2011 Appl. Phys. Lett. 98 243104
[64]	Baaske M D, Foreman M R, Vollmer F 2014 Nat. Nanotechnology 9 933
[65]	65 Wu Y Q, Vollmer F 2014 Cavity-Enhanced Spectroscopy and Sensing (New York: Springer) 179 pp323-349
[66]	Yang L, Carmon T, Min B, Spillane S M, Vahala K J 2005 Appl. Phys. Lett. 86 091114
[67]	Yang J, Guo L J 2006 IEEE J. Sel. Top. Quant. 12 143
[68]	He L, zdemir S K, Zhu J, Yang L 2010 Phys. Rev. A 82 053810
[69]	He L, zdemir S K, Xiao Y F, Yang L 2010 IEEE J. Quantum Electron 46 1626
[70]	He L, zdemir S K, Zhu J, Yang L 2010 Opt. Lett. 35 256
[71]	He L, zdemir S K, Yang L 2013 Laser. Photon. Rev. 7 60
[72]	Salzenstein P, Mortier M, Srier-Brault H, Henriet R, Coillet A, Chembo Y K, Rasoloniaina A, Dumeige Y, Fron P
[73]	He L, zdemir S K, Zhu J, Monifi F, Yilmaz H, Yang L 2013 New J. Phys. 15 073030
[74]	Lei F, Peng B, zdemir S K, Long G L, Yang L 2014 Appl. Phys. Lett. 105 101112
[75]	Bradley J D, Hosseini E S, Purnawirman P, Su Z, Adam T N, Leake G, Coolbaugh D, Watts M R 2014 Opt. Express 22 12226
[76]	Rasoloniaina A, Huet V, Nguyen T K N, Le Cren E, Mortier M, Michely L, Dumeige Y, Fron P 2014 Sci. Rep. 4 4023
[77]	zdemir S K, He L, Zhu J, Monifi F, Kim W, Kenechukwu O, Yilmaz H, Huang S, Yang L 2013 SPIE OPTO 86270N
[78]	zdemir S K, Zhu J, Yang X, Peng B, Yilmaz H, He L, Monifi F, Huang S H, Long G L, Yang L 2014 Proc. Natl. Acad. Sci. 111 E3836
[79]	Spillane S M, Kippenberg T J, Vahala K J 2002 Nature 415 621
[80]	80 Boyd R W 2003 Nonlinear Optics (2nd ed.) (London: Academic Press)
[81]	Kippenberg T J, Spillane S M, Armani D K, Vahala K J 2004 Opt. Lett. 29 1224
[82]	Rong H, Jones R, Liu A, Cohen O, Hak D, Fang A, Paniccia M 2005 Nature 433 725
[83]	Troccoli M, Belyanin A, Capasso F, Cubukcu E, Sivco D L, Cho A Y 2005 Nature 433 845
[84]	Sennaroglu A, Kiraz A, Dndar M, Kurt A, Demirel A 2007 Opt. Lett. 32 2197
[85]	Jiang X F, Xiao Y F, Yang Q F, Shao L, Clements W R, Gong Q 2013 Appl. Phys. Lett. 103 101102
[86]	Li B B, Xiao Y F, Yan M Y, Clements W R, Gong Q 2013 Opt. Lett. 38 1802
[87]	Li B B, Clements W R, Yu X C, Shi K, Gong Q, Xiao Y F 2014 Proc. Natl. Acad. Sci. 111 14657
[88]	Vahala K J 2003 Nature 424 839
[89]	Gorodetsky M L, Ilchenko V S 1999 J. Opt. Soc. Am. B 16 147
[90]	Bogaerts W, De Heyn P, van Vaerenbergh T, De Vos K, Kumar Selvaraja S, Claes T, Dumon P, Bienstman P, van Thourhout D, Baets R 2012 Laser. Photon. Rev. 6 47
[91]	Zou C L, Dong C H, Cui J M, Sun F W, Yang Y, Wu X W, Han Z F, Guo G C 2012 Sci. China-Phys. Mech. Astron. 42 1155 (in Chinese) [邹长铃, 董春华, 崔金明, 孙方稳, 杨勇, 吴晓伟, 韩正甫, 郭光灿 2012 中国科学: 物理学力学天文学 42 1155]
[92]	Xiao Y F, Zou C L, Li Y, Dong C H, Han Z F, Gong Q 2010 Frontiers of Optoelectronics in China 3 109
[93]	McLachlan A D, Meyer F P 1987 Appl. Opt. 26 1728
[94]	Cai M, Painter O, Vahala K J 2000 Phys. Rev. Lett. 85 74
[95]	Little B E, Chu S T, Haus H A, Foresi J, Laine J P 1997 J. Lightwave Technol. 15 998
[96]	Gorodetsky M, Ilchenko V 1994 Opt. Commun. 113 133
[97]	Yariv A 2000 Electron. Lett. 36 321
[98]	Dumeige Y, Trebaol S, Ghisa L, Nguyn T K N, Tavernier H, Fron P 2008 J. Opt. Soc. Am. B 25 2073
[99]	Weiss D, Sandoghdar V, Hare J, Lefevre-Seguin V, Raimond J M, Haroche S 1995 Opt. Lett. 20 1835
[100]	Mazzei A, Gtzinger S, Menezes L d S, Zumofen G, Benson O, Sandoghdar V 2007 Phys. Rev. Lett. 99 173603
[101]	He L, zdemir S K, Zhu J, Yang L 2010 Appl. Phys. Lett. 96 221101
[102]	Yi X, Xiao Y F, Liu Y C, Li B B, Chen Y L, Li Y, Gong Q 2011 Phys. Rev. A 83 023803
[103]	Rong H, Xu S, Cohen O, Raday O, Lee M, Sih V, Paniccia M 2008 Nat. Photonics 2 170
[104]	Stiles P L, Dieringer J A, Shah N C, Van Duyne R P 2008 Annu. Rev. Anal. Chem. 1 601
[105]	Grudinin I S, Maleki L 2008 J. Opt. Soc. Am. B 25 594
[106]	Liang D, Fiorentino M, Okumura T, Chang H H, Spencer D T, Kuo Y H, Fang A W, Dai D, Beausoleil R G, Bowers J E 2009 Opt. Express 17 20355
[107]	Lu T, Yang L, Carmon T, Min B 2011 IEEE J. Quantum. Electron. 47 320
[108]	Chistiakova M V, Armani A M 2012 Opt. Lett. 37 4068
[109]	Monifi F, demir S, Friedlein J, Yang L 2013 Photonic. Tech. L. 25 1458
[110]	Agrawal G P 2007 Nonlinear Fiber Optics (4th ed.) (London: Academic Press)
[111]	Wiersig J 2014 Phys. Rev. Lett. 112 203901
[112]	Yu X C, Li B B, Wang P, Tong L, Jiang X F, Li Y, Gong Q, Xiao Y F 2014 Adv. Mater. 26 7462
[113]	Xu Q, Lipson M 2007 Opt. Express 15 924
[114]	Monifi F, zdemir S K, Yang L 2013 Appl. Phys. Lett. 103 181103
[115]	Peng Y C, Zhao X W, Fu G S, Wang Y L 2004 Chin. J. Quan. Elec. 21 273 (in Chinese) [彭英才, Zhao X W, 傅广生, 王英龙 2004 量子电子学报 21 273]
[116]	Zhang C Y, Liu X Y, Ma F Y, Zhu W B, Wang L J Huang Y, Yang Y, Wang S, Xiao J, Che K, Du Y 2006 Acta Opt. Sin. 26 111 (in Chinese) [张春玉, 刘星元, 马凤英, 朱万彬, 王立军2006 光学学报26 111]
[117]	Huang Y, Yang Y, Wang S, Xiao J, Che K, Du Y 2009 Sci. China. E 52 3447
[118]	Dong C H, Shen Z, Zou C L, Guo G C 2015 Sci. China. Phys. Mech. Astron. 58 050308

Cited By

[1]	Szymanski W W, Nagy A, Czitrovszky A, Jani P 2002 Meas. Sci. Technol. 13 303
[2]	Van D M, Tchebotareva A, Orrit M, Lippitz M, Berciaud S, Lasne D, Cognet L, Lounis B 2006 PCCP 8 3486
[3]	Burg T P, Godin M, Knudsen S M, Shen W, Carlson G, Foster J S, Babcock K, Manalis S R 2007 Nature 446 1066
[4]	Vollmer F, Arnold S 2008 Nat. Methods 5 591
[5]	Vollmer F, Arnold S, Keng D 2008 Proc. Natl. Acad. Sci. 105 20701
[6]	Fan X, White I M, Shopova S I, Zhu H, Suter J D, Sun Y 2008 Anal. Chim. Acta 620 8
[7]	Naik A, Hanay M, Hiebert W, Feng X, Roukes M 2009 Nat. Nanotechnology 4 445
[8]	Zhu J, zdemir S K, Xiao Y F, Li L, He L, Chen D R, Yang L 2010 Nat. Photonics 4 46
[9]	He L, zdemir S K, Zhu J, Kim W, Yang L 2011 Nat. Nanotechnology 6 428
[10]	Vollmer F, Yang L
[11]	Yurt A, Daaboul G G, Connor J H, Goldberg B B, Unl M S 2012 Nanoscale 4 715
[12]	Wang W, Tao N 2013 Anal. Chem. 86 2
[13]	Colvin V L 2003 Nat. Biotechnology 21 1166
[14]	Hoet P H, Brske-Hohlfeld I, Salata O V 2004 J. Nanobiotechnology 2 12
[15]	Alivisatos P 2004 Nat. Biotechnology 22 47
[16]	Storhoff J J, Lucas A D, Garimella V, Bao Y P, Mller U R 2004 Nat. Biotechnology 22 883
[17]	Cheng M M C, Cuda G, Bunimovich Y L, Gaspari M, Heath J R, Hill H D, Mirkin C A, Nijdam A J, Terracciano R, Thundat T, Ferrari M 2006 Curr. Opin. Chem. Biol. 10 11
[18]	Sinha R, Kim G J, Nie S, Shin D M 2006 Mol. Cancer. Ther. 5 1909
[19]	De M, Ghosh P S, Rotello V M 2008 Adv. Mater. 20 4225
[20]	Smith A M, Nie S 2009 Accounts Chem. Res. 43 190
[21]	Dai S X, Lu L W, Tao G M, Xu Y S, Yin D M, Niu X K, Zhang W 2012 Laser Optoelectronics Progress. 49 080001 (in Chinese) [戴世勋, 路来伟, 陶光明, 许银生, 尹冬梅, 牛雪珂, 张巍 2012 激光与光电子学进展 49 080001]
[22]	Betzig E, Trautman J, Harris T, Weiner J, Kostelak R 1991 Science 251 1468
[23]	Zhang J, Dong L, Yu S H 2015 Sci. Bull. 60 785
[24]	Seydack M 2005 Biosens. Bioelectron. 20 245
[25]	Liu T G, Zhang F, Meng Z (in Chinese) [刘铁根, 张凡, 孟卓 2005 光学技术 31 96]
[26]	Wei Q, Qi H, Luo W, Tseng D, Ki S J, Wan Z, Grcs Z, Bentolila L A, Wu T T, Sun R, Ozcan A 2013 ACS Nano 7 9147
[27]	Plakhotnik T, Palm V 2001 Phys. Rev. Lett. 87 183602
[28]	Knollenber R G
[29]	Boyer D, Tamarat P, Maali A, Lounis B, Orrit M 2002 Science 297 1160
[30]	Lindfors K, Kalkbrenner T, Stoller P, Sandoghdar V 2004 Phys. Rev. Lett. 93 037401
[31]	Patolsky F, Zheng G, Hayden O, Lakadamyali M, Zhuang X, Lieber C M 2004 Proc. Natl. Acad. Sci. 101 14017
[32]	Choi Y, Moody I S, Sims P C, Hunt S R, Corso B L, Perez I, Weiss G A, Collins P G 2012 Science 335 319
[33]	Arlett J L, Myers E B, Roukes M L 2011 Nat. Nanotechnology 6 203
[34]	Yue X J, Hong T S, Yang Z, Huang S P 2013 Chin. Sci. Bull. 58 821
[35]	Zhang L, Song Z D 2014 Sci. China-Phys. Mech. Astron. 57 880
[36]	Lu X K, Guo M T, Su J P, Gong Q X, Wu J K, Liu J L, Chen M, Ma F Y 2013 Acta Phys. Sin. 62 084208 (in Chinese) [卢小可, 郭茂田, 苏建坡, 弓巧侠, 武进科, 刘建立, 陈明, 马凤英 2013 物理学报 62 084208]
[37]	Nie W J, Lan Y H, Li Y Zhu S Y 2014 Sci. China-Phys. Mech. Astron. 57 2276
[38]	Svedendahl M, Verre R, Kll M 2014 Light: Science Applications 3 e220
[39]	Li W F, Du J J, Wen R J, Yang P F, Li G, Zhang T C 2014 Acta. Phys. Sin. 63 244205 (in Chinese) [李文芳, 杜金锦, 文瑞娟, 杨鹏飞, 李刚, 张天才 2014 物理学报 63 244205]
[40]	Sheng Y B, Liu J, Zhao S Y, Zhou L
[41]	Du J J, Li W F, Wen R J, Li G, Zhang T C 2013 Acta Phys. Sin. 62 194203 (in Chinese) [杜金锦, 李文芳, 文瑞娟, 李刚, 张天才 2013 物理学报 62 194203]
[42]	Wang C, He L Y, Zhang Y, Ma H Q, Zhang R 2013 Sci. China-Phys. Mech. Astron. 56 2054
[43]	Arnold S, Khoshsima M, Teraoka I, Holler S, Vollmer F 2003 Opt. Lett. 28 272
[44]	Hunt H K, Armani A M
[45]	Vollmer F, Braun D, Libchaber A, Khoshsima M, Teraoka I, Arnold S 2002 Appl. Phys. Lett. 80 4057
[46]	Sun Y, Fan X 2011 Anal. Bioanal. Chem. 399 205
[47]	Armani A M, Kulkarni R P, Fraser S E, Flagan R C, Vahala K J 2007 Science 317 783
[48]	Washburn A L, Luchansky M S, Bowman A L, Bailey R C 2009 Anal. Chem. 82 69
[49]	Shopova S, Rajmangal R, Nishida Y, Arnold S 2010 Rev. Sci. Instrum. 81 103110
[50]	Lu T, Lee H, Chen T, Herchak S, Kim J H, Fraser S E, Flagan R C, Vahala K 2011 Proc. Natl. Acad. Sci. 108 5976
[51]	Santiago-Cordoba M A, Boriskina S V, Vollmer F, Demirel M C 2011 Appl. Phys. Lett. 99 073701
[52]	Zhu J, zdemir S K, He L, Chen D R, Yang L 2011 Opt. Express 19 16195
[53]	Dantham V R, Holler S, Kolchenko V, Wan Z, Arnold S 2012 Appl. Phys. Lett. 101 043704
[54]	Santiago-Cordoba M A, Cetinkaya M, Boriskina S V, Vollmer F, Demirel M C 2012 J. Biophotonics 5 629
[55]	Kim W, zdemir S K, Zhu J, Monifi F, Coban C, Yang L 2012 Opt. Express 20 29426
[56]	Yi X, Xiao Y F, Feng Y, Qiu D Y, Fan J Y, Li Y, Gong Q 2012 J. Appl. Phys. 111 114702
[57]	Lin S, Crozier K B 2013 ACS Nano 7 1725
[58]	Dantham V R, Holler S, Barbre C, Keng D, Kolchenko V, Arnold S 2013 Nano Lett. 13 3347
[59]	Swaim J D, Knittel J, Bowen W P 2013 Appl. Phys. Lett. 102 183106
[60]	Shao L, Jiang X F, Yu X C, Li B B, Clements W R, Vollmer F, Wang W, Xiao Y F, Gong Q 2013 Adv. Mater. 25 5616
[61]	Knittel J, Swaim J D, McAuslan D L, Brawley G A, Bowen W P 2013 Sci. Rep. 3 2947
[62]	Wang T, Cao C, Wang C 2013 Sci. China Inform. Sci. 56 1
[63]	Shopova S, Rajmangal R, Holler S, Arnold S 2011 Appl. Phys. Lett. 98 243104
[64]	Baaske M D, Foreman M R, Vollmer F 2014 Nat. Nanotechnology 9 933
[65]	65 Wu Y Q, Vollmer F 2014 Cavity-Enhanced Spectroscopy and Sensing (New York: Springer) 179 pp323-349
[66]	Yang L, Carmon T, Min B, Spillane S M, Vahala K J 2005 Appl. Phys. Lett. 86 091114
[67]	Yang J, Guo L J 2006 IEEE J. Sel. Top. Quant. 12 143
[68]	He L, zdemir S K, Zhu J, Yang L 2010 Phys. Rev. A 82 053810
[69]	He L, zdemir S K, Xiao Y F, Yang L 2010 IEEE J. Quantum Electron 46 1626
[70]	He L, zdemir S K, Zhu J, Yang L 2010 Opt. Lett. 35 256
[71]	He L, zdemir S K, Yang L 2013 Laser. Photon. Rev. 7 60
[72]	Salzenstein P, Mortier M, Srier-Brault H, Henriet R, Coillet A, Chembo Y K, Rasoloniaina A, Dumeige Y, Fron P
[73]	He L, zdemir S K, Zhu J, Monifi F, Yilmaz H, Yang L 2013 New J. Phys. 15 073030
[74]	Lei F, Peng B, zdemir S K, Long G L, Yang L 2014 Appl. Phys. Lett. 105 101112
[75]	Bradley J D, Hosseini E S, Purnawirman P, Su Z, Adam T N, Leake G, Coolbaugh D, Watts M R 2014 Opt. Express 22 12226
[76]	Rasoloniaina A, Huet V, Nguyen T K N, Le Cren E, Mortier M, Michely L, Dumeige Y, Fron P 2014 Sci. Rep. 4 4023
[77]	zdemir S K, He L, Zhu J, Monifi F, Kim W, Kenechukwu O, Yilmaz H, Huang S, Yang L 2013 SPIE OPTO 86270N
[78]	zdemir S K, Zhu J, Yang X, Peng B, Yilmaz H, He L, Monifi F, Huang S H, Long G L, Yang L 2014 Proc. Natl. Acad. Sci. 111 E3836
[79]	Spillane S M, Kippenberg T J, Vahala K J 2002 Nature 415 621
[80]	80 Boyd R W 2003 Nonlinear Optics (2nd ed.) (London: Academic Press)
[81]	Kippenberg T J, Spillane S M, Armani D K, Vahala K J 2004 Opt. Lett. 29 1224
[82]	Rong H, Jones R, Liu A, Cohen O, Hak D, Fang A, Paniccia M 2005 Nature 433 725
[83]	Troccoli M, Belyanin A, Capasso F, Cubukcu E, Sivco D L, Cho A Y 2005 Nature 433 845
[84]	Sennaroglu A, Kiraz A, Dndar M, Kurt A, Demirel A 2007 Opt. Lett. 32 2197
[85]	Jiang X F, Xiao Y F, Yang Q F, Shao L, Clements W R, Gong Q 2013 Appl. Phys. Lett. 103 101102
[86]	Li B B, Xiao Y F, Yan M Y, Clements W R, Gong Q 2013 Opt. Lett. 38 1802
[87]	Li B B, Clements W R, Yu X C, Shi K, Gong Q, Xiao Y F 2014 Proc. Natl. Acad. Sci. 111 14657
[88]	Vahala K J 2003 Nature 424 839
[89]	Gorodetsky M L, Ilchenko V S 1999 J. Opt. Soc. Am. B 16 147
[90]	Bogaerts W, De Heyn P, van Vaerenbergh T, De Vos K, Kumar Selvaraja S, Claes T, Dumon P, Bienstman P, van Thourhout D, Baets R 2012 Laser. Photon. Rev. 6 47
[91]	Zou C L, Dong C H, Cui J M, Sun F W, Yang Y, Wu X W, Han Z F, Guo G C 2012 Sci. China-Phys. Mech. Astron. 42 1155 (in Chinese) [邹长铃, 董春华, 崔金明, 孙方稳, 杨勇, 吴晓伟, 韩正甫, 郭光灿 2012 中国科学: 物理学力学天文学 42 1155]
[92]	Xiao Y F, Zou C L, Li Y, Dong C H, Han Z F, Gong Q 2010 Frontiers of Optoelectronics in China 3 109
[93]	McLachlan A D, Meyer F P 1987 Appl. Opt. 26 1728
[94]	Cai M, Painter O, Vahala K J 2000 Phys. Rev. Lett. 85 74
[95]	Little B E, Chu S T, Haus H A, Foresi J, Laine J P 1997 J. Lightwave Technol. 15 998
[96]	Gorodetsky M, Ilchenko V 1994 Opt. Commun. 113 133
[97]	Yariv A 2000 Electron. Lett. 36 321
[98]	Dumeige Y, Trebaol S, Ghisa L, Nguyn T K N, Tavernier H, Fron P 2008 J. Opt. Soc. Am. B 25 2073
[99]	Weiss D, Sandoghdar V, Hare J, Lefevre-Seguin V, Raimond J M, Haroche S 1995 Opt. Lett. 20 1835
[100]	Mazzei A, Gtzinger S, Menezes L d S, Zumofen G, Benson O, Sandoghdar V 2007 Phys. Rev. Lett. 99 173603
[101]	He L, zdemir S K, Zhu J, Yang L 2010 Appl. Phys. Lett. 96 221101
[102]	Yi X, Xiao Y F, Liu Y C, Li B B, Chen Y L, Li Y, Gong Q 2011 Phys. Rev. A 83 023803
[103]	Rong H, Xu S, Cohen O, Raday O, Lee M, Sih V, Paniccia M 2008 Nat. Photonics 2 170
[104]	Stiles P L, Dieringer J A, Shah N C, Van Duyne R P 2008 Annu. Rev. Anal. Chem. 1 601
[105]	Grudinin I S, Maleki L 2008 J. Opt. Soc. Am. B 25 594
[106]	Liang D, Fiorentino M, Okumura T, Chang H H, Spencer D T, Kuo Y H, Fang A W, Dai D, Beausoleil R G, Bowers J E 2009 Opt. Express 17 20355
[107]	Lu T, Yang L, Carmon T, Min B 2011 IEEE J. Quantum. Electron. 47 320
[108]	Chistiakova M V, Armani A M 2012 Opt. Lett. 37 4068
[109]	Monifi F, demir S, Friedlein J, Yang L 2013 Photonic. Tech. L. 25 1458
[110]	Agrawal G P 2007 Nonlinear Fiber Optics (4th ed.) (London: Academic Press)
[111]	Wiersig J 2014 Phys. Rev. Lett. 112 203901
[112]	Yu X C, Li B B, Wang P, Tong L, Jiang X F, Li Y, Gong Q, Xiao Y F 2014 Adv. Mater. 26 7462
[113]	Xu Q, Lipson M 2007 Opt. Express 15 924
[114]	Monifi F, zdemir S K, Yang L 2013 Appl. Phys. Lett. 103 181103
[115]	Peng Y C, Zhao X W, Fu G S, Wang Y L 2004 Chin. J. Quan. Elec. 21 273 (in Chinese) [彭英才, Zhao X W, 傅广生, 王英龙 2004 量子电子学报 21 273]
[116]	Zhang C Y, Liu X Y, Ma F Y, Zhu W B, Wang L J Huang Y, Yang Y, Wang S, Xiao J, Che K, Du Y 2006 Acta Opt. Sin. 26 111 (in Chinese) [张春玉, 刘星元, 马凤英, 朱万彬, 王立军2006 光学学报26 111]
[117]	Huang Y, Yang Y, Wang S, Xiao J, Che K, Du Y 2009 Sci. China. E 52 3447
[118]	Dong C H, Shen Z, Zou C L, Guo G C 2015 Sci. China. Phys. Mech. Astron. 58 050308

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