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Doublet mechanics (DM) is applied to materials with dispersing property. The wave equation in multi-layered skin tissue is obtained through the method of DM in this article. By changing the Poisson ratio in melanoma skin tissue, the growth and spread of melanoma (Breslow thickness), the internode distance, the reflection coefficients of the longitudinal waves incident vertically in the multi-layered skin model are calculated. And the acoustic velocity and acoustic attenuation coefficient changing with tissue parameters are also calculated. The results show that we can synthesize the change of the number of the minimal reflection coefficient, acoustic velocity and attenuation coefficient to discriminate cancerous skin from normal skin within a certain frequency.
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Keywords:
- doublet mechanics /
- skin tissue /
- ultrasonic tissue characterization
[1] Manschot J F M 1985 Ph. D. Dissertation (Nijmegen: Katholieke University)
[2] Odland G F 1991 Physiology, Biochemistry, and Molecular Biology of the Skin (New York: Oxford University Press) pp3-62
[3] Jemal A, Siegel R, Xu J, Ward E 2010 CA Cancer J. Clin. 60 277
[4] Raveh Tilleman T, Tilleman M, Neumann H 2004 Optimization of Incisions in Cutaneous Surgery Including Mohs' Micrographic Surgery (Rotterdam: Erasmus University Rotterdam) p105
[5] Robins S, Cotran R, Kumar V 1979 Pathologic Basis of Disease (Philadelphia: WB Saunders Company) p1333
[6] Ferrari M 1997 Advances in Doublet Mechanics (Berlin: Springer) p214
[7] Liu J, Ferrari M 2002 Dis Markers 18 175
[8] Liu J, Ferrari M, Rokhlin S I, Sedmak D D 2004 U.S. Patent 20040064050
[9] Wu J R, Layman C 2004 J. Acoust. Soc. Am. 115 893
[10] Layman C, Wu J R 2004 J. Acoust. Soc. Am. 116 1244
[11] Jin Y F, Zhang J, Fang J, Ferrari M 2004 Chin. Phys. Lett. 21 1562
[12] Jin Y F, Xiong C Y, Fang J, Ferrari M 2009 Chin. Phys. Lett. 26 084601
[13] Kojic M, Vlastelica I, Decuzzi P, Grank V T, Ferrrari M 2011 Comput. Methods Appl. M. 200 1446
[14] Ferrari M 2000 Biomed. Microdevices 2 273
[15] Jiang X, Liu X Z, W J R 2009 Chin. Phys. Lett. 26 074301
[16] Jiang X, Liu X Z, Gong X F, Zhang F, Wu R R 2011 J. Acoust. Soc. Am. 130 4117
[17] Jiang X, Liu X Z 2009 Tech. Acoust. 28(Pt.3) 73 (in Chinese) [江鑫, 刘晓宙 2009 声学技术 28(Pt.3) 73]
[18] Xue H H, Liu X Z, Gong X F, Zhang D 2005 Acta Phys. Sin. 54 5233 (in Chinese)[薛洪惠, 刘晓宙, 龚秀芬, 章东 2005 物理学报 54 5233]
[19] Li J L, Liu X Z, Gong X F 2006 Acta Phys. Sin. 55 2809 (in Chinese)[李俊伦, 刘晓宙, 龚秀芬 2006 物理学报 55 2809]
[20] Gentile F, Sakamoto J, Righetti R, Decuzzi P, Ferrrari M 2011 J. Biomed. Sci. Eng. 4 362
[21] Sakamoto J, Decuzzi P, Gentile F, Rokhlin S I, Wang L 2006 BioMEMS and Biomedical Nanotechnology (New York: Springer) pp461-504
[22] Sakamoto J H 2005 Ph. D. Dissertation (Columbus: Ohio State University)
[23] Lee R C, Dougherty W 2003 IEEE Trans. Dielectr. Electr. Insul. 10 810
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[1] Manschot J F M 1985 Ph. D. Dissertation (Nijmegen: Katholieke University)
[2] Odland G F 1991 Physiology, Biochemistry, and Molecular Biology of the Skin (New York: Oxford University Press) pp3-62
[3] Jemal A, Siegel R, Xu J, Ward E 2010 CA Cancer J. Clin. 60 277
[4] Raveh Tilleman T, Tilleman M, Neumann H 2004 Optimization of Incisions in Cutaneous Surgery Including Mohs' Micrographic Surgery (Rotterdam: Erasmus University Rotterdam) p105
[5] Robins S, Cotran R, Kumar V 1979 Pathologic Basis of Disease (Philadelphia: WB Saunders Company) p1333
[6] Ferrari M 1997 Advances in Doublet Mechanics (Berlin: Springer) p214
[7] Liu J, Ferrari M 2002 Dis Markers 18 175
[8] Liu J, Ferrari M, Rokhlin S I, Sedmak D D 2004 U.S. Patent 20040064050
[9] Wu J R, Layman C 2004 J. Acoust. Soc. Am. 115 893
[10] Layman C, Wu J R 2004 J. Acoust. Soc. Am. 116 1244
[11] Jin Y F, Zhang J, Fang J, Ferrari M 2004 Chin. Phys. Lett. 21 1562
[12] Jin Y F, Xiong C Y, Fang J, Ferrari M 2009 Chin. Phys. Lett. 26 084601
[13] Kojic M, Vlastelica I, Decuzzi P, Grank V T, Ferrrari M 2011 Comput. Methods Appl. M. 200 1446
[14] Ferrari M 2000 Biomed. Microdevices 2 273
[15] Jiang X, Liu X Z, W J R 2009 Chin. Phys. Lett. 26 074301
[16] Jiang X, Liu X Z, Gong X F, Zhang F, Wu R R 2011 J. Acoust. Soc. Am. 130 4117
[17] Jiang X, Liu X Z 2009 Tech. Acoust. 28(Pt.3) 73 (in Chinese) [江鑫, 刘晓宙 2009 声学技术 28(Pt.3) 73]
[18] Xue H H, Liu X Z, Gong X F, Zhang D 2005 Acta Phys. Sin. 54 5233 (in Chinese)[薛洪惠, 刘晓宙, 龚秀芬, 章东 2005 物理学报 54 5233]
[19] Li J L, Liu X Z, Gong X F 2006 Acta Phys. Sin. 55 2809 (in Chinese)[李俊伦, 刘晓宙, 龚秀芬 2006 物理学报 55 2809]
[20] Gentile F, Sakamoto J, Righetti R, Decuzzi P, Ferrrari M 2011 J. Biomed. Sci. Eng. 4 362
[21] Sakamoto J, Decuzzi P, Gentile F, Rokhlin S I, Wang L 2006 BioMEMS and Biomedical Nanotechnology (New York: Springer) pp461-504
[22] Sakamoto J H 2005 Ph. D. Dissertation (Columbus: Ohio State University)
[23] Lee R C, Dougherty W 2003 IEEE Trans. Dielectr. Electr. Insul. 10 810
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