早期乳腺肿瘤的超宽带微波稳健波束形成成像检测系统

肖夏; 宋航; 王梁; 王宗杰; 路红

doi:10.7498/aps.63.194102

摘要

提出了一种基于自主设计小型超宽带天线的微波稳健波束形成（RCB）成像肿瘤检测系统. 仿真结果表明，该检测系统对肿瘤反射信号有很高的敏感度. 在简单平面模型和核磁共振成像图（MRI）导出模型中进行仿真检测实验，并将天线阵列接收信号用RCB算法进行成像处理. 从乳房重构图像中能够得到正确的肿瘤位置及大小信息，实现了平面模型中最小直径3 mm和MRI导出模型中最小直径4 mm的肿瘤检测，证实了该检测系统用于早期乳腺肿瘤检测的可行性.

关键词:

Abstract

An ultra-wideband (UWB) microwave robust Capon beamforming imaging system is presented based on a self-designed compact UWB antenna for early breast cancer detection. Simulation results show that the proposed detection system is sensitive to tumor response. Simulated tumor detection experiments are carried out in both simple planar breast model and magnetic resonance imagining (MRI)-derived model using the antenna array. Robust Capon beamforming algorithm is employed to reconstruct the breast image. Successful detection of 3-mm-diameter tumor is achieved in the planar model and the same detection result of 4-mm-diameter tumor is achieved in the MRI-derived model. The right information of the tumor can be obtained from the imaging results, which demonstrates the feasibility of the proposed system in early breast cancer detection.

Keywords:

作者及机构信息

1.
天津大学, 电子信息工程学院, 天津 300072;

2.
天津医科大学附属肿瘤医院放射科, 乳腺癌防治国家教育部重点实验室, 天津 300060

基金项目: 国家自然科学基金（批准号：61271323）和毫米波国家重点实验室开放基金（批准号：K200913）资助的课题.

Authors and contacts

1.
School of Electronic Information Engineering, Tianjin University, Tianjin 300072, China;

2.
Department of Radiology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast Cancer Prevention and Therapy of Ministry of Education, Tianjin 300060, China

Funds: Project supported by the National Natural Science Foundation of China (Grant No. 61271323), and the Open Project from State Key Laboratory of Millimeter Waves, China (Grant No. K200913).

参考文献

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[3]	Xiao X, Xu L, Liu B Y 2013 Acta Phys. Sin. 62 044105(in Chinese) [肖夏, 徐立, 刘冰雨 2013 物理学报 62 044105]
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[5]	Klemm M, Craddock I J, Leendertz J A, Preece A W, Benjamin R 2009 IEEE Trans. Antennas Propag. 57 1692
[6]	Fear E C, Bourqui J, Curtis C, Mew D, Docktor B, Romano C 2013 IEEE Trans. Microw. Theory Tech. 61 2119
[7]	Liu G D, Zhang Y R 2011 Acta Phys. Sin. 60 074303(in Chinese) [刘广东, 张业荣 2011 物理学报 60 074303]
[8]	Ryu K S, Kishk A A 2011 IEEE Trans. Antennas Propag. 59 3738
[9]	Chen Y F, Craddock I J, Kosmas P, Ghavami M, Rapajic P 2010 IEEE J. Sel. Top. Signal Process. 4 187
[10]	Lim H B, Nhung N T T, Li E P, Thang N D 2008 IEEE Trans. Biomed. Eng. 55 1697
[11]	Xie Y, Guo B, Xu L Z, Li J, Stoica P 2006 IEEE Trans. Biomed. Eng. 53 1647
[12]	Liu B Y, Xiao X, Liu X 2011International Conference on Control, Automation and Systems Engineering, Singapore, July 30-31, 2011, p1
[13]	Gibbins D, Klemm M, Craddock I J, Leenderts J A, Preece A, Benjamin R 2010 IEEE Trans. Antennas Propag. 58 665
[14]	Fear E C, Li X, Hagness S C, Stuchly M A 2002 IEEE Trans. Biomed. Eng. 49 812
[15]	Li X, Hagness S C, Choi M K, van der Weide D W 2003 IEEE Antennas Wirel. Propag. Lett. 2 259
[16]	Sill J M, Fear E C, Westwick D 2005 IEEE Trans. Microw. Theory Tech. 53 3312
[17]	Wang Y, Bakar A, Bialkowski M 2011 Microw. Opt. Technol. Lett. 53 830
[18]	Li X Y, Sit Y L, Zwirello L, Zwick T 2013 Microw. Opt. Technol. Lett. 55 105
[19]	Zhang J J, Fear E C, Johnston R H 2009 Microw. Opt. Technol. Lett. 51 275
[20]	Bourqui J, Okoniewski M, Fear E C 2010 IEEE Trans. Antennas Propag. 58 2318
[21]	Amineh R K, Ravan M, Trehan A, Nikolova N K 2011 IEEE Trans. Antennas Propag. 59 928
[22]	Bourqui J, Fear E C 2012 IEEE Antennas Wirel. Propag. Lett. 11 1614
[23]	Xiao X, Kikkawa T 2008 Appl. Surf. Sci. 255 597
[24]	Li J, Stoica P, Wang Z 2003 IEEE Trans. Signal Process. 51 1702

施引文献

[1]	Xiao X, Xu L, Li Q W 2013 Chin. Phys. B 22 094101
[2]	Fear E C, Hagness S C, Meaney P M, Okinoiewski M, Stuchly M A 2002 IEEE Microw. Mag. 3 48
[3]	Xiao X, Xu L, Liu B Y 2013 Acta Phys. Sin. 62 044105(in Chinese) [肖夏, 徐立, 刘冰雨 2013 物理学报 62 044105]
[4]	Li X, Bond E J, Van Veen D B, Hagness S C 2005 IEEE Antennas Propag. Mag. 47 19
[5]	Klemm M, Craddock I J, Leendertz J A, Preece A W, Benjamin R 2009 IEEE Trans. Antennas Propag. 57 1692
[6]	Fear E C, Bourqui J, Curtis C, Mew D, Docktor B, Romano C 2013 IEEE Trans. Microw. Theory Tech. 61 2119
[7]	Liu G D, Zhang Y R 2011 Acta Phys. Sin. 60 074303(in Chinese) [刘广东, 张业荣 2011 物理学报 60 074303]
[8]	Ryu K S, Kishk A A 2011 IEEE Trans. Antennas Propag. 59 3738
[9]	Chen Y F, Craddock I J, Kosmas P, Ghavami M, Rapajic P 2010 IEEE J. Sel. Top. Signal Process. 4 187
[10]	Lim H B, Nhung N T T, Li E P, Thang N D 2008 IEEE Trans. Biomed. Eng. 55 1697
[11]	Xie Y, Guo B, Xu L Z, Li J, Stoica P 2006 IEEE Trans. Biomed. Eng. 53 1647
[12]	Liu B Y, Xiao X, Liu X 2011International Conference on Control, Automation and Systems Engineering, Singapore, July 30-31, 2011, p1
[13]	Gibbins D, Klemm M, Craddock I J, Leenderts J A, Preece A, Benjamin R 2010 IEEE Trans. Antennas Propag. 58 665
[14]	Fear E C, Li X, Hagness S C, Stuchly M A 2002 IEEE Trans. Biomed. Eng. 49 812
[15]	Li X, Hagness S C, Choi M K, van der Weide D W 2003 IEEE Antennas Wirel. Propag. Lett. 2 259
[16]	Sill J M, Fear E C, Westwick D 2005 IEEE Trans. Microw. Theory Tech. 53 3312
[17]	Wang Y, Bakar A, Bialkowski M 2011 Microw. Opt. Technol. Lett. 53 830
[18]	Li X Y, Sit Y L, Zwirello L, Zwick T 2013 Microw. Opt. Technol. Lett. 55 105
[19]	Zhang J J, Fear E C, Johnston R H 2009 Microw. Opt. Technol. Lett. 51 275
[20]	Bourqui J, Okoniewski M, Fear E C 2010 IEEE Trans. Antennas Propag. 58 2318
[21]	Amineh R K, Ravan M, Trehan A, Nikolova N K 2011 IEEE Trans. Antennas Propag. 59 928
[22]	Bourqui J, Fear E C 2012 IEEE Antennas Wirel. Propag. Lett. 11 1614
[23]	Xiao X, Kikkawa T 2008 Appl. Surf. Sci. 255 597
[24]	Li J, Stoica P, Wang Z 2003 IEEE Trans. Signal Process. 51 1702

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