A non-collinear laser beam combination based on Brillouin amplification was proposed. The influence of non-collinear Brillouin amplification on the combination efficiency was analyzed and discussed theoretically. It was shown that the efficiency of 80% can be achieved with the angle between the Stokes and the pump limited in the range of 90 mrad. According to the theoretical results, a four-beam non-collinear combination experiment was designed and carried out. The output energy of 189 mJ at 10 Hz was achieved with the energies of the four pumps being 70.4, 71.3 , 78.9 and 70.1 mJ， respectively. In order to simplify the scheme and reduce the optical loss, a construction of SBS cell for non-collinear combination of multiple beams was also designed.