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Accurate detection of liver fibrosis stage and fibrosis procession is crucial for assessing prognosis and candidacy for treatment of patients with chronic hepatic disease. A significant need exists for developing a noninvasive technique for quantitative detection of liver fibrosis stage. Magnetic resonance elasto-graphy (MRE) is one of the most repidly advancing technologies for classifying the liver fibrosis. This study establishes a platform for liver fibrosis classification, and discusses some details in developing stimulator and displacement-phase imaging pulse. At last, the preliminary result and analysis of phantom experiment are given, which would form a basis for subsequent research on phantom MRE and its clinic application.
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Keywords:
- magnetic resonance elasto-graphy /
- liver fibrosis /
- phantom /
- shear wave
[1] Huwart L, Peeters F, Sinkus R 2006 NMR Biomed. 19 173
[2] Tian Y, Fan Z P, Gu H Y 2007 World J. Gastroenterol. 24 2626 (in Chinese) [田 艳、范竹萍、顾海燕 2007 世界华人消化杂志 24 2626]
[3] Meng Y, Talwalkar J, Glaser J, Manduca A, Grimm C, Rossman J, Fidler L, Ehman L 2007 Clin. Gastroenterol. Hepatol. 10 1207
[4] Huwart L, Peeters F, Sinkus R, Annet L, Salameh N, Beek L, Horsmans Y, Beers B 2006 NMR Biomed. 19 173
[5] Hamer O, Aguirre D, Casola G 2006 Radiography 26 1637
[6] Piccinino F, Sagnelli G, Pasquale G, Giusti G 1986 J. Hepatol. 2 165
[7] Bravo A, Sheth S, Chopra S 2001 New Eng. J. Med. 344 495
[8] Kelleher B, Afdhal N 2005 Clin. Liver. Dis. 9 667
[9] Rouviere O, Meng Y, Dresner A, Rossman J, Burgart L, Fidler J, Ehman R 2006 Radiology 240 440
[10] Peeters F 2005 Proceedings of the International Society for Magnetic Resonance in Medicine Miami , USA, May 7—13, 2005 p339
[11] Rouviere O, Meng Y, Dresner A, Rossman J, Burgart L, Fidler J, Ehman R 2005 Proceedings of the International Society for Magnetic Resonance in Medicine Miami, USA, May 7—13, 2005 p340
[12] Klatt D, Asbach P, Rump J, Papazoglou S, Somasundaram R, Modrow J, Braun J, Sack I 2006 Invest. Radiol. 41 841
[13] Muthupillai R, Lomas D, Rossman P, Greenleaf J, Manduca A, Ehman R 1995 Science 269 1854
[14] Shadi F, Zhou X H, Xu H H, Royston J, Magin L 2007 Magn. Reson. Im. 25 94
[15] Cheng J, Ni C, Zhuang T G 2006 Chin. Sci. Bull. 51 781 (in Chinese) [陈 俊、倪 成、庄天戈 2006 科学通报 51 781]
[16] Wang H Z, Wen Z Q, Huang Y, Zhang X L, Cheng H Y, Li G Y 2008 Chin. J. Med. Image Tech. 11 1833 (in Chinese) [汪红志、温增庆、黄 勇、张学龙、程红岩、李鲠颖 2008 中国医 学影像技术 11 1833] 〖17] Xu L, Gao P Y, Lin Y 2006 Chin. J. Med. Phys. 23 253
[17] Thomas R, Richard L, An K N 2003 J. Biome. Chan. 36 1917
[18] McKnight A, Kugel J, Rossman P, Manduca A, Hartmann L, Ehman R 2002 AJR 178 1411
[19] Sinkus R, Tanter M, Xydeas T, Catheline S, Bercoff J, Fink M 2005 Magn. Reso. Imag. 23 159
[20] Plewes B, Bishop J, Samani A, Sciarretta J 2000 Phys. Med. Biol. 45 1591
[21] Bao S L, Gao S, Zhang S G, Zhou K, Zu Z L 2008 Chin. Phys. B 17 328
[22] Wang H, Li G Y 2005 Acta Phys. Sin. 54 1431 (in Chinese) [王 鹤、李鲠颖 2005 物理学报 54 1431]
[23] Luo J, Ren T T, Sun X P, Zhan M S 2009 Chin. Phys. 11 4711
[24] Oida T, Amano A, Matsuda T 2004 International Conference on Informatics Research for Development of Knowledge Society Infrastructure (ICKS' 04 ) Japan, 1—2 March, 2004 p57
[25] Oudry J, Chen J, Glaser K, Miette V, Sandrin L,Ehman R 2009 J. Magn. Reson. Im. 30 1145
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[1] Huwart L, Peeters F, Sinkus R 2006 NMR Biomed. 19 173
[2] Tian Y, Fan Z P, Gu H Y 2007 World J. Gastroenterol. 24 2626 (in Chinese) [田 艳、范竹萍、顾海燕 2007 世界华人消化杂志 24 2626]
[3] Meng Y, Talwalkar J, Glaser J, Manduca A, Grimm C, Rossman J, Fidler L, Ehman L 2007 Clin. Gastroenterol. Hepatol. 10 1207
[4] Huwart L, Peeters F, Sinkus R, Annet L, Salameh N, Beek L, Horsmans Y, Beers B 2006 NMR Biomed. 19 173
[5] Hamer O, Aguirre D, Casola G 2006 Radiography 26 1637
[6] Piccinino F, Sagnelli G, Pasquale G, Giusti G 1986 J. Hepatol. 2 165
[7] Bravo A, Sheth S, Chopra S 2001 New Eng. J. Med. 344 495
[8] Kelleher B, Afdhal N 2005 Clin. Liver. Dis. 9 667
[9] Rouviere O, Meng Y, Dresner A, Rossman J, Burgart L, Fidler J, Ehman R 2006 Radiology 240 440
[10] Peeters F 2005 Proceedings of the International Society for Magnetic Resonance in Medicine Miami , USA, May 7—13, 2005 p339
[11] Rouviere O, Meng Y, Dresner A, Rossman J, Burgart L, Fidler J, Ehman R 2005 Proceedings of the International Society for Magnetic Resonance in Medicine Miami, USA, May 7—13, 2005 p340
[12] Klatt D, Asbach P, Rump J, Papazoglou S, Somasundaram R, Modrow J, Braun J, Sack I 2006 Invest. Radiol. 41 841
[13] Muthupillai R, Lomas D, Rossman P, Greenleaf J, Manduca A, Ehman R 1995 Science 269 1854
[14] Shadi F, Zhou X H, Xu H H, Royston J, Magin L 2007 Magn. Reson. Im. 25 94
[15] Cheng J, Ni C, Zhuang T G 2006 Chin. Sci. Bull. 51 781 (in Chinese) [陈 俊、倪 成、庄天戈 2006 科学通报 51 781]
[16] Wang H Z, Wen Z Q, Huang Y, Zhang X L, Cheng H Y, Li G Y 2008 Chin. J. Med. Image Tech. 11 1833 (in Chinese) [汪红志、温增庆、黄 勇、张学龙、程红岩、李鲠颖 2008 中国医 学影像技术 11 1833] 〖17] Xu L, Gao P Y, Lin Y 2006 Chin. J. Med. Phys. 23 253
[17] Thomas R, Richard L, An K N 2003 J. Biome. Chan. 36 1917
[18] McKnight A, Kugel J, Rossman P, Manduca A, Hartmann L, Ehman R 2002 AJR 178 1411
[19] Sinkus R, Tanter M, Xydeas T, Catheline S, Bercoff J, Fink M 2005 Magn. Reso. Imag. 23 159
[20] Plewes B, Bishop J, Samani A, Sciarretta J 2000 Phys. Med. Biol. 45 1591
[21] Bao S L, Gao S, Zhang S G, Zhou K, Zu Z L 2008 Chin. Phys. B 17 328
[22] Wang H, Li G Y 2005 Acta Phys. Sin. 54 1431 (in Chinese) [王 鹤、李鲠颖 2005 物理学报 54 1431]
[23] Luo J, Ren T T, Sun X P, Zhan M S 2009 Chin. Phys. 11 4711
[24] Oida T, Amano A, Matsuda T 2004 International Conference on Informatics Research for Development of Knowledge Society Infrastructure (ICKS' 04 ) Japan, 1—2 March, 2004 p57
[25] Oudry J, Chen J, Glaser K, Miette V, Sandrin L,Ehman R 2009 J. Magn. Reson. Im. 30 1145
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